ArticleFrontiers in medicine2026
3% diquafosol sodium combined with 0.1% fluorometholone for postoperative dry eye in pterygium patients with preoperative tear deficiency: a pilot retrospective study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: To evaluate the clinical efficacy and safety of 3% diquafosol sodium combined with 0.1% fluorometholone for postoperative dry eye in pterygium patients with preoperative tear deficiency. Methods: This single-center retrospective study included 82 pterygium patients (82 eyes) with preoperative tear deficiency who underwent pterygium excision combined with limbal stem cell transplantation. Patients were divided into an observation group (diquafosol + fluorometholone, Results: Eighty patients completed follow-up (41 in observation group, 39 in control group). At 4 weeks postoperatively, the observation group showed significantly longer BUT, lower CFS and OSDI scores, and higher SIt values compared to the control group (all Conclusion: In this pilot study, the combination of 3% diquafosol sodium and 0.1% fluorometholone showed preliminary evidence of improving tear film stability, repairing ocular surface damage, and alleviating dry eye symptoms in pterygium patients with preoperative tear deficiency, without significantly affecting IOP. Its efficacy appeared superior to sodium hyaluronate combined with fluorometholone. These findings support further investigation in larger, longer-term randomized controlled trials.
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