ArticleFrontiers in medicine2026
The value of speckle tracking echocardiography in early identification of subclinical cardiac involvement in patients with multiple myeloma: a pilot retrospective study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Multiple myeloma (MM) is frequently associated with cardiac involvement, particularly myocardial amyloidosis. Current gold-standard diagnostic modalities include cardiac MRI, and endomyocardial biopsy. Speckle-tracking echocardiography (STE) enables detection of subclinical left ventricular dysfunction prior to overt structural or functional deterioration. This pilot retrospective study explored the association between GLS and clinically defined cardiac involvement in MM patients, in the absence of gold-standard confirmation. Methodology: We conducted a retrospective analysis of 20 consecutive MM patients, stratified into two groups: cardiac involvement (CI; Results: Absolute GLS was significantly lower in the cardiac involvement group (median 9.6% vs. 16.9%, Conclusion: In this study, STE-derived GLS demonstrated promising diagnostic performance for identifying cardiac involvement in MM patients. However, given the small sample size, these findings should be considered hypothesis-generating. External validation in large, prospective, multi-center cohorts is required before any clinical implementation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.