Evidence map›Paper›PMID 42454001›Full record

Trial reportJournal of pain research2026

Preoperative Transcutaneous Electrical Acupoint Stimulation Alleviates Postoperative Pain and Improves Sleep Quality in Breast Cancer Patients with Preoperative Sleep Disturbance: A Partially Randomized Controlled Trial.

Can Ma, Hong Xiong, Wenchao Fu, Shihua Lv, Lijuan Zhang, Dengming Zhao, Cong Hu, Xiuli Wang, Wenzhi Li

Abstract readCase ReportsClinical Trial
In one paragraph

Trial report in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Can MaThe Key Laboratory of Anesthesiology and Intensive Care Research of Heilongjiang Province, Harbin, Heilongjiang, People's Republic of China.
Hong XiongThe Third People's Hospital of Chengdu, Chengdu, Sichuan, People's Republic of China.
Wenchao FuThe Key Laboratory of Anesthesiology and Intensive Care Research of Heilongjiang Province, Harbin, Heilongjiang, People's Republic of China.
Shihua LvThe Key Laboratory of Anesthesiology and Intensive Care Research of Heilongjiang Province, Harbin, Heilongjiang, People's Republic of China.
Lijuan ZhangThe Key Laboratory of Anesthesiology and Intensive Care Research of Heilongjiang Province, Harbin, Heilongjiang, People's Republic of China.
Dengming ZhaoThe Key Laboratory of Anesthesiology and Intensive Care Research of Heilongjiang Province, Harbin, Heilongjiang, People's Republic of China.
Cong HuThe Key Laboratory of Anesthesiology and Intensive Care Research of Heilongjiang Province, Harbin, Heilongjiang, People's Republic of China.
Xiuli WangDepartment of Anesthesiology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People's Republic of China.
Wenzhi LiThe Key Laboratory of Anesthesiology and Intensive Care Research of Heilongjiang Province, Harbin, Heilongjiang, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Preoperative sleep disturbance exacerbates postoperative pain and delays recovery. Transcutaneous electrical acupoint stimulation (TEAS) may alleviate insomnia and pain. This trial evaluated preoperative TEAS on postoperative pain, sleep, and intraoperative hemodynamics in breast cancer patients with preoperative sleep disturbance. Patients and Methods: Fifty-nine breast cancer patients (aged 37-70 years) were stratified by Pittsburgh Sleep Quality Index (PSQI): PSQI < 6 were assigned to the non-randomized control group (Group C, n = 26), while patients with PSQI ≥ 6 were randomly allocated (1:1) to the sleep disturbance group (Group S, n = 16) or the TEAS group (Group T, n = 17). TEAS (2/100 Hz, 8-12 mA, 30 min) was delivered pre-anesthesia at LI4, HT7, and PC6. Pain was assessed via Numerical Rating Scale (NRS) at 4, 24, 48, and 72 h postoperatively. Sleep was measured with Athens Insomnia Scale (AIS). Intraoperative systolic blood pressure variability (sdSBP, cvSBP) was recorded. Results: In observational comparisons, Group S exhibited elevated NRS scores at 24, 48, and 72 h vs Group C ( Conclusion: Preoperative TEAS significantly attenuates postoperative pain and improves sleep in breast cancer patients with preoperative sleep disturbance, possibly associated with reduced intraoperative blood pressure variability. Preoperative sleep quality may predict postoperative outcomes.

Indexed as

autonomic nervous systembreast cancerpostoperative painsleep disturbancetranscutaneous electrical acupoint stimulation

Identifiers

PMID42454001
PMCPMC13367492

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.