Evidence map›Paper›PMID 42453983›Full record

ArticleFrontiers in cellular and infection microbiology2026

C3 in

Filippo Bertolasi, Sandro Sacchi, Alessandro Vezzi, Gabriele Sales, Anita Ferri, Davide Malagoli, Nicola Franchi

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Filippo BertolasiDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Sandro SacchiDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Alessandro VezziDepartment of Biology, University of Padova, Padova, Italy.
Gabriele SalesDepartment of Biology, University of Padova, Padova, Italy.
Anita FerriDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Davide MalagoliDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Nicola FranchiDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

C3 is the central effector of the complement system and one of the most conserved molecules of metazoan innate immunity. Despite its relevance, little is known about complement components in Lophotrochozoa. Here, we characterise the C3 ortholog of the freshwater gastropod

Indexed as

Complement C3GastropodaAnimalsGene Expression ProfilingHemocytesImmunity, InnateLipopolysaccharidesPhylogenyComplement C3LipopolysaccharidesC3cell clearancecomplement evolutioncomplement systemdevelopmentimmunityinvertebrate

Identifiers

PMID42453983
PMCPMC13365339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.