Evidence map›Paper›PMID 42453982›Full record

ArticleFrontiers in cellular and infection microbiology2026

The GspCD-dependent type II secretion system promotes necrotizing soft tissue infection caused by

Yuka Tonosaki, Kohei Yamazaki, Shota Owada, Kei Yamaguchi, Takashige Kashimoto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuka TonosakiLaboratory of Veterinary Public Health, School of Veterinary Medicine, Kitasato University, Aomori, Japan.
Kohei YamazakiLaboratory of Veterinary Public Health, School of Veterinary Medicine, Kitasato University, Aomori, Japan.
Shota OwadaLaboratory of Veterinary Public Health, School of Veterinary Medicine, Kitasato University, Aomori, Japan.
Kei YamaguchiLaboratory of Veterinary Public Health, School of Veterinary Medicine, Kitasato University, Aomori, Japan.
Takashige KashimotoLaboratory of Veterinary Public Health, School of Veterinary Medicine, Kitasato University, Aomori, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Necrotizing soft tissue infections (NSTIs) are fulminant bacterial diseases characterized by rapid tissue destruction, systemic deterioration, and high mortality.

Indexed as

Aeromonas hydrophilaBacterial ProteinsGram-Negative Bacterial InfectionsSoft Tissue InfectionsType II Secretion SystemsAnimalsDisease Models, AnimalDNA Transposable ElementsFemaleMiceMutagenesis, InsertionalNecrosisVirulenceVirulence FactorsBacterial ProteinsDNA Transposable ElementsType II Secretion SystemsVirulence FactorsAeromonas hydrophilaextracellular protein secretionnecrotizing soft tissue infectiontype II secretion systemvirulence

Identifiers

PMID42453982
PMCPMC13364864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.