Therapeutic potential of

Caroline Mooki, Oladunni M Ayodele, Saheed Sabiu, Adeyemi O Aremu, Makhotso Lekhooa

Abstract read

In one paragraph

Article in In silico pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Caroline MookiPreclinical Drug Development Platform, Faculty of Health Sciences, North-West University, Private Bag X6001, Potchefstroom, 2521 South Africa.

Oladunni M AyodeleDepartment of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, P.O. Box 1334, Durban, 4000 South Africa.

Saheed SabiuDepartment of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, P.O. Box 1334, Durban, 4000 South Africa.

Adeyemi O AremuCentre of Excellence in Indigenous Knowledge Systems, Faculty of Natural and Agricultural Sciences, North-West University, Private Bag X2046, Mmabatho, 2745 South Africa.

Makhotso LekhooaPreclinical Drug Development Platform, Faculty of Health Sciences, North-West University, Private Bag X6001, Potchefstroom, 2521 South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medicinal plants offer promising multi-target therapeutic agents due to their diverse bioactive compounds. This study explored LC-MS profiling, network pharmacology, molecular docking, and molecular dynamics simulation to investigate the potential antidepressant-related mechanisms of Graphical abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s40203-026-00689-2.

Indexed as

BiodiversityComputational analysisNetwork pharmacologyNeurochemicalWild dagga

Identifiers

PMID42453925

DOI10.1007/s40203-026-00689-2

PMCPMC13365280

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.