Evidence map›Paper›PMID 42453898›Full record

ArticleDiscovery immunology2026

Dendritic-cell diversity in equine blood revealed by single-cell transcriptomics.

Ambre Baillou, Marius Botos, Simone Oberhaensli, Iva Cvitas, Sigridur Jonsdottir, Anja Ziegler, Francisco Brito, Artur Summerfield, Eliane Marti, Stephanie C Talker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discovery immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ambre BaillouInstitute of Virology and Immunology, Bern, Switzerland.ORCID https://orcid.org/0009-0006-8890-0485
Marius BotosInstitute of Virology and Immunology, Bern, Switzerland.
Simone OberhaensliInterfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.
Iva CvitasDepartment of Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Sigridur JonsdottirDepartment of Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Anja ZieglerDepartment of Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Francisco BritoInstitute of Virology and Immunology, Bern, Switzerland.
Artur SummerfieldInstitute of Virology and Immunology, Bern, Switzerland.
Eliane MartiDepartment of Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Stephanie C TalkerInstitute of Virology and Immunology, Bern, Switzerland.ORCID https://orcid.org/0000-0002-3966-6251

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Detailed classification of equine dendritic cells (DC) is necessary to address various research questions, such as the role of DC subsets in immune-mediated diseases of horses. Methods: We applied single-cell RNA sequencing (scRNA-seq) on DC enriched from the blood of two horses. Results: All main DC subsets were detected by key gene expression, including conventional DC type 1 (cDC1; Conclusion: Our atlas of equine blood DC is a valuable resource for comparative analyses, and it forms the foundation for understanding the involvement of distinct DC subsets in infections and immune-mediated pathologies.

Indexed as

cDC1cDC2 subsetsDC3equine blood dendritic cellspDCsingle-cell RNA-seqtDC

Identifiers

PMID42453898
PMCPMC13367329

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.