Primary classical Hodgkin lymphoma of breast presenting as recurrent breast abscess in a non-lactating woman: a case report and literature review.

Introduction: Primary breast lymphoma (PBL) is an exceptionally rare entity, accounting for only 0.3-0.5% of all breast lymphomas. The majority of reported cases are diffuse large B- cell lymphoma. Clinical and imaging findings often mimic breast carcinoma, and diagnosis is usually confirmed incidentally by biopsy. Recurrent breast abscesses in non-lactating women or in men should raise suspicion of underlying malignancy. Case presentation: We report the case of a 55-year-old non-lactating woman who presented to the surgical clinic with a non-healing wound following the incision and drainage of a recurrent breast abscess. A second excisional biopsy revealed primary classical Hodgkin lymphoma of the right breast, mixed cellularity subtype. The patient was treated with the BV-AD regimen, resulting in an excellent clinical response and complete wound healing. Conclusion: This case highlights the importance of considering malignant etiologies, including rare lymphomas, in patients with recurrent breast abscesses. It underscores the diagnostic challenges posed by overlapping features with breast carcinoma and contributes to the limited literature on primary classical Hodgkin lymphoma of the breast.