ArticleEcology and evolution2026
Feeding Strategy Shapes the Evolution of the Hyaluronidase Gene Family in Medicinal Leeches.
Article in Ecology and evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Hyaluronidase plays a critical role as a "spreading factor" during blood-feeding in leeches, yet the molecular evolution of this gene family remains poorly understood. In this study, we combined phylogenetic reconstruction, selective pressure analyses, and transcriptome-based expression profiling to investigate the evolutionary characteristics of the hyaluronidase gene family across eight medicinal leech species representing hematophagous and non-hematophagous lineages. Our results showed that all hematophagous species retained five complete hyaluronidase gene family members (
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