ArticleCureus2026
Long-Term Outcome of Immunosuppression in a Patient With Immunoglobulin A Nephropathy and Serum-Positive Antineutrophil Cytoplasmic Antibodies.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The concurrent occurrence of immunoglobulin A nephropathy (IgAN) and serum-positive antineutrophil cytoplasmic antibodies (ANCA) is a rare clinical entity frequently associated with more severe disease progression. Without appropriate intervention, affected individuals may rapidly advance to end-stage kidney disease (ESKD), necessitating renal replacement therapy. Early initiation of intensive induction immunosuppressive therapy has the potential to enhance renal outcomes, which can be maintained over time with suitable maintenance regimens. In this report, we describe the management of a patient with pre-existing chronic kidney disease (CKD) and impaired baseline renal function who was treated with cyclophosphamide for induction and azathioprine for maintenance for crescentic IgAN and serum-positive ANCA. This approach resulted in substantial improvement in renal function, which was preserved over a 55-month follow-up period.
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