ArticleOpen forum infectious diseases2026
Outcomes of the Three-month Weekly Isoniazid With Rifapentine (3HP) Versus the Six-month Isoniazid Preventive Therapy (6H) Among People Newly Enrolled in HIV Care in Western Kenya.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Tuberculosis Incidence and Predictors Among People Living With HIV After Isoniazid-Rifapentine (3HP) Preventive Therapy in Ethiopia: A Retrospective Cohort Study.Journal of tropical medicine · 2026Article
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8 authors.
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Abstract
Background: In trials, 3-month weekly rifapentine and isoniazid (3HP) showed higher adherence and completion than the 6-month daily isoniazid (6H) regimen for TB preventive treatment (TPT). However, programmatic outcome data remain limited. Methods: We evaluated the TPT cascade among people with HIV (PWH) aged ≥15 years newly enrolled in HIV care in western Kenya. Initiation and completion of 6H (Jan-Sept 2022) were compared to 3HP (Oct 2022-Sept 2023) using χ Results: Of 1930 PWH (median age 33 years [IQR=27-41]), 65.8% were female, and 19.5% had advanced HIV disease (AHD) at enrollment. Overall, 1922 (99.6%) were screened for active TB, of whom 1790 (97.5%) were TPT-eligible; 1577 (88.1%) of these initiated TPT. TPT initiation was higher with 3HP than 6H (89.8% vs 84.2%; Conclusions: TPT initiation was significantly higher after 3HP implementation. However, 3HP completion was similar to 6H. Targeted interventions are needed to support 3HP completion, particularly in PWH with AHD.
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