Evidence map›Paper›PMID 42453773›Full record

ReviewExperimental and therapeutic medicine2026

Ovarian toxic effects of micro- and nanoplastics (Review).

Shuoran Zhao, Weiting Yuan, Ping Li, Jieyong Yang

Abstract readReview
In one paragraph

Review in Experimental and therapeutic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shuoran ZhaoDepartment of Critical Care Medicine, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.
Weiting YuanEmergency Department, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.
Ping LiDepartment of Critical Care Medicine, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.
Jieyong YangDepartment of Obstetrics and Gynecology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong 264100, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microplastics and nanoplastics (MNPs) have become widespread contaminants with notable impacts on reproductive health. MNPs have been found in human specimens, including follicle fluid, causing concerns regarding their negative impact on female fertility. The present review aimed to comprehensively examine the ovarian deleterious impacts of MNPs, and to analyze their toxicological mechanisms, impact on folliculogenesis and oocyte quality, transgenerational effects and influencing factors. Previous evidence suggests that MNPs can trigger oxidative stress, inflammatory responses, disruption of endocrine function, programmed cell death, endoplasmic reticulum stress, membrane structural damage, epigenetic modifications and DNA lesions in the ovary, resulting in impaired folliculogenesis, disrupted steroidogenesis and reduced reproductive capacity. The present review emphasized the impact of the MNP polymer type, size and surface characteristics on ovarian reproductive toxicity, and highlights some knowledge gaps that require attention, providing a reference for deeper understanding and mitigation of MNPs-induced ovarian toxicity.

Indexed as

endocrine disruptionfolliculogenesismicroplasticsnanoplasticsoocyte qualityovarian toxicityoxidative stress

Identifiers

PMID42453773
PMCPMC13365865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.