Evidence map›Paper›PMID 42453670›Full record

ArticleFrontiers in nutrition2026

Functional instant tea from black tea waste fiber: effects of extraction conditions on bioactive composition and

Neriman Ezgi Cifte, Gokhan Gorgisen, Emre Taskın, Beyza Bızıkcı, Buse Sonmez, Serap Namli, Mecit Halil Oztop

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Neriman Ezgi CifteDepartment of Food Engineering, Middle East Technical University, Ankara, Türkiye.
Gokhan GorgisenDepartment of Medical Biology, Gülhane Faculty of Medicine, University of Health Sciences, Ankara, Türkiye.
Emre TaskınDogadan Food Products Industry and Marketing Inc., Ankara, Türkiye.
Beyza BızıkcıDepartment of Food Engineering, Middle East Technical University, Ankara, Türkiye.
Buse SonmezDepartment of Food Engineering, Middle East Technical University, Ankara, Türkiye.
Serap NamliDepartment of Food Engineering, Middle East Technical University, Ankara, Türkiye.
Mecit Halil OztopDepartment of Food Engineering, Middle East Technical University, Ankara, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Black tea processing generates large amounts of waste fiber that still retains considerable levels of bioactive compounds. In this study, black tea waste fiber was valorized for the production of instant tea powders, and the influence of extraction conditions on both bioactive composition and anticancer activity was investigated. Methods: Instant tea powders were produced using hot extraction (100 °C, 6 min) and cold extraction (25 °C, 2 h). Catechins, gallic acid, caffeine, theanine, theaflavin and thearubigins were quantified. Anticancer activity was evaluated by the MTT assay using prostate cancer cell lines (PC3, 22Rv1 and LNCaP), glioblastoma cell lines (U87MG and A172) and the breast cancer cell line MCF7. Results: Hot extraction resulted in significantly higher levels of catechins, condensed phenolics and theanine ( Discussion: These findings demonstrate that black tea waste fiber can serve as a valuable raw material for functional instant tea production and highlight the importance of extraction conditions in shaping both the bioactive profile and biological activity of instant tea products derived from tea processing residues.

Indexed as

anticancer activitybioactive compoundsblack tea waste fibercatechinscold extractionhot extractioninstant teaMTT assay

Identifiers

PMID42453670
PMCPMC13364970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.