Evidence map›Paper›PMID 42453561›Full record

ArticleMindfulness2024

Mindfulness Training Has Long-term Therapeutic Benefits in Women with Irritable Bowel Syndrome.

Susan A Gaylord, Olafur S Palsson, Eric L Garland, J Douglas Mann, Karen Bluth, William E Whitehead, Keturah R Faurot

Abstract read
In one paragraph

Article in Mindfulness, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Beyond Chronic Stress: Daily Stress Is Associated With Symptoms in Irritable Bowel Syndrome.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Susan A GaylordProgram on Integrative Medicine, Department of Physical Medicine and Rehabilitation, Campus Box #7200, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, 27514.
Olafur S PalssonDepartment of Medicine, Center for Functional Gastrointestinal and Motility Disorders and Division of Gastroenterology and Hepatology, School of Medicine, 101 Manning Drive, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, 27514.
Eric L GarlandCenter on Mindfulness and Integrative Health Intervention Development, University of Utah, Salt Lake City, UT, USA.
J Douglas MannDepartment of Neurology, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, 27514.
Karen BluthDepartment of Psychiatry, School of Medicine, 105 Smith Level Rd, Chapel Hill, NC, United States, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. 27516.
William E WhiteheadDepartment of Medicine, Center for Functional Gastrointestinal and Motility Disorders and Division of Gastroenterology and Hepatology, School of Medicine, 101 Manning Drive, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, 27514.
Keturah R FaurotProgram on Integrative Medicine, Department of Physical Medicine and Rehabilitation, Campus Box #7200, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, 27514.ORCID 0000-0001-6122-782

Funding

UNC Research Fellowship in Complementary and Alternative MedicineT32AT003378 · NCCIH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Keturah Ruth Faurot, Susan Gaylord · 2007 to 2026
$7.8M
PSYCHOPHYSIOLOGY OF IRRITABLE BOWEL SYNDROMER01DK031369 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WHITEHEAD, WILLIAM E · 1986 to 2012
$6.3M
Gastrointestinal Biopsychosocial Research CenterR24DK067674 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WHITEHEAD, WILLIAM E · 2004 to 2008
$4.5M
Mindfulness for Irritable Bowel SyndromeR21AT003619 · NCCIH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GAYLORD, SUSAN · 2006 to 2008
$571k
NCCIH NIH HHS R21 AT003619NCCIH NIH HHS T32 AT003378NIDDK NIH HHS R01 DK031369NIDDK NIH HHS R24 DK067674
6 · The paper itself

Abstract

Objective: Mindfulness training (MT) has been shown to have substantial therapeutic effects on irritable bowel syndrome (IBS) symptom severity, health-related quality of life, and psychological symptoms at 3 months following an 8-week group MT intervention. This study reports a secondary analysis to examine the long-term trajectory of change in these IBS symptoms. Methods: This study analyzed 6- and 12-month follow-up data collected in a randomized controlled pilot study involving 75 adult women meeting Rome II criteria for IBS assigned to 8 weekly 2-hour sessions plus one half-day intensive of either a group Mindfulness Training (MT) or a validated IBS support group (SG). Outcome measures included the IBS Symptom Severity Scale (IBS-SSS), the IBS-Quality of Life (IBS-QOL) and Visceral Sensitivity Index (VSI) questionnaires, and the Brief Symptom Inventory-18 psychological distress measure. Measures were mailed to all participants who attended at least one treatment session. Analysis included mixed effects models comparing the trajectory of change over time between groups. Results: At six months follow-up, MT patients had significantly lower mean IBS-SSS scores than SG patients (-M 123.79 points vs. -51.82 points, respectively, p=0.004). At 12-month follow-up, effects were attenuated, with IBS-SSS scores of -88.93 (p=0.001) for MT and -353.63 (p=0.158) for SG participants, with a clinically important between-group difference of 61 points (p=0.). VSI scores significantly improved at both 6- and 12-month follow-up compared to baseline, for the MT group only. Anxiety and depression significantly improved at six months, in the MT group only. Conclusions: Beneficial effects of an 8-week MT program tailored for IBS persist for up to 12 months after the training.

Indexed as

clinical trialirritable bowel syndromelong-term follow-upMindfulnessMindfulness-based stress reduction

Identifiers

PMID42453561
PMCPMC13367915

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.