ArticleSurgical case reports2026
Early Postoperative Recurrence and Systemic Metastases Following Curative Resection of Primary Melanoma of the Lung.
Article in Surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
introductionPrimary melanoma of the lung (PML) is exceedingly rare, accounting for approximately 0.01% of lung cancers. Because cutaneous melanoma may undergo spontaneous regression, a solitary pulmonary melanoma may represent either a true primary lesion or a metastasis from an occult regressed cutaneous primary. Therefore, rigorous exclusion of extrapulmonary primary sites is essential. PML is generally associated with a poor prognosis, and its biology and optimal management remain incompletely defined. Here, we report a case of PML with early systemic relapse after curative resection and provide a brief review of the literature. CASE PRESENTATION: A 57-year-old woman was referred to our department (Department of General Thoracic Surgery, Osaka International Cancer Institute) for surgical management after an abnormal chest shadow was detected on routine health screening. Chest CT revealed a 2.0-cm irregular nodule in the left lower lobe with ipsilateral hilar lymphadenopathy.
conclusionsThis case highlights the diagnostic challenges and aggressive clinical course of PML. Thorough exclusion of extrapulmonary primary sites and comprehensive histopathologic and molecular assessment are required. Given the high risk of early systemic relapse, further investigation of multidisciplinary strategies, including perioperative systemic therapy, is warranted.
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