ArticlePatient preference and adherence2026
Analysis of Medication-Related Burden and Associated Factors Among Elderly Patients with Coronary Heart Disease: A Cross-Sectional Study.
Article in Patient preference and adherence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This cross-sectional study sought to examine the current level of medication-related burden (MRB) in elderly individuals with coronary heart disease (CHD) and to explore its key determinants. The findings are intended to inform strategies for optimizing medication management, mitigating MRB, and enhancing treatment adherence. Methods: A cross-sectional survey was conducted amongst 231 elderly patients diagnosed with CHD who were admitted to the cardiology ward of tertiary hospital in Hefei from January to March 2026. Data collection was performed using three assessment tools: the Chinese version of the Living with Medicines Questionnaire-3 (C-LMQ-3), the Chinese version of the Beliefs about Medicines Questionnaire (C-BMQ), and a reliable and valid Medication Literacy Scale. Statistical procedures included descriptive statistics, univariate tests, and multiple linear regression analyses. Results: Mean overall scores from the C-LMQ-3 and Visual Analogue Scale (VAS) both indicated moderate MRB among participants. Regression analysis indicated that medication adverse reactions, utilization of medication assistance devices, acquisition of medication-related health education, medication beliefs, and medication literacy were independent predictors of MRB (all P < 0.05). Conclusion: MRB levels among elderly CHD patients are moderate and are associated with various modifiable factors. Medical practitioners should implement holistic approaches to reduce MRB, with particular attention to enhancing medication literacy and addressing medication beliefs, alongside minimizing adverse drug events, encouraging the use of medication support tools, and reinforcing medication education.
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