ReviewJournal of multidisciplinary healthcare2026
Mindfulness-Based Spiritual Interventions for Patients with Advanced Cancer Receiving Palliative Care: A Systematic Review of Randomized Controlled Trials.
Review in Journal of multidisciplinary healthcare, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Psychological and spiritual distress are highly prevalent in patients with advanced cancer, yet conventional interventions often fail to address their interconnected nature. While mindfulness-based interventions (MBIs) are widely used in oncology, their integration with spiritual or meaning-centered components remains insufficiently synthesized in high-level evidence. Objective: This review aimed to evaluate the effectiveness and characteristics of mindfulness-based spiritual interventions on psychological and spiritual outcomes in patients with advanced and palliative cancer. Methods: A PRISMA-guided systematic review of randomized controlled trials (RCTs) was conducted using PubMed, Scopus, and CINAHL databases (2015-2025). Eligible studies included adult patients with cancer receiving mindfulness-based interventions incorporating explicit spiritual, religious, or existential components. Methodological quality was appraised using the Joanna Briggs Institute checklist, and findings were synthesized using qualitative descriptive and narrative synthesis. Results: Thirteen RCTs were included. The interventions were categorized into (1) hospital-based interventions and (2) remotely delivered interventions. Across these categories, five outcome domains were identified: psychological well-being (anxiety, depression, distress, quality of life), spiritual well-being (meaning, peace, faith, existential acceptance), attrition and treatment engagement, intervention acceptability, and mixed or inconsistent findings. Conclusion: Mindfulness-based interventions that explicitly integrate spiritual or meaning-centered elements offer a comprehensive approach to addressing multidimensional distress in advanced cancer. These findings suggest that integrative psycho-spiritual care models may be beneficial in oncology and palliative care. Future research should prioritize standardized intervention frameworks and mechanism-driven evaluation across diverse populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.