ArticleTzu chi medical journal
Survival outcomes of endometrial cancer patients with lymphovascular space invasion: A multicenter, retrospective cohort study.
Article in Tzu chi medical journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Objectives: This study aimed to evaluate the prognostic impact of lymphovascular space invasion (LVSI) on treatment outcomes and survival in patients with endometrial cancer (EC). Materials and Methods: We conducted a multicenter, retrospective study of 298 EC patients who underwent hysterectomy-based surgery between January 2011 and June 2021. Clinical and pathological data, including LVSI status, were collected. Cox regression and multivariate analyses were performed to assess recurrence, progression-free survival (PFS), and overall survival (OS), with adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) reported. Results: LVSI-positive patients ( Conclusion: LVSI is an independent predictor of recurrence in EC but may not significantly affect PFS or OS after adjusting for treatment. These findings highlight the need for tailored adjuvant therapy in LVSI-positive patients and further research to clarify its prognostic value.
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