Evidence map›Paper›PMID 42453417›Full record

ReviewActa pharmaceutica Sinica. B2026

Machine learning reshapes the paradigm of nanomedicine research.

Ziye Wei, Shijie Zhuo, Yixin Zhang, Lianlian Wu, Xiang Gao, Song He, Xiaochen Bo, Wenhu Zhou

Abstract readReview
In one paragraph

Review in Acta pharmaceutica Sinica. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ziye WeiXiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.
Shijie ZhuoXiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.
Yixin ZhangAcademy of Military Medical Sciences, Beijing 100850, China.
Lianlian WuAcademy of Military Medical Sciences, Beijing 100850, China.
Xiang GaoState Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Song HeAcademy of Military Medical Sciences, Beijing 100850, China.
Xiaochen BoAcademy of Military Medical Sciences, Beijing 100850, China.
Wenhu ZhouXiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanodrug delivery systems (NDDS) have demonstrated outstanding performance in drug delivery due to their efficient delivery capacity, targeting ability, and biocompatibility. However, the development of nanomedicines still heavily relies on the expertise of formulation scientists and extensive trial-and-error experiments. Despite the abundance of data in nanoscience, traditional biological research often struggles to effectively process, analyze, and utilize these datasets, limiting nanomedicine studies to a "one-to-one" approach. Against this backdrop, the rapid growth of artificial intelligence (AI) and machine learning (ML) offers a new paradigm for nanomedicine research. Unlike traditional statistical analyses and mathematical models, AI and ML provide deeper insights into big data, enhancing the efficiency of nanomedicine development while steering the field toward more intelligent and more precise research approaches. This review focuses on milestone studies that use ML to reshape nanomedicine research from a pharmaceutics perspective, highlighting how data-driven ML models can guide new directions in nanomedicine development.

Indexed as

Artificial intelligenceData scienceDeep learningDrug delivery systemsMachine learningNanoinformaticsNanomedicinePharmaceutics

Identifiers

PMID42453417
PMCPMC13366331

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.