Tailored Ion Release of Polycaprolactone and Calcium Silicate Composite Fibers Attenuates Neutrophil Extracellular Trap Formation for Dentin-Pulp Complex Regeneration.

Jeong-Hyun Ryu, En Shi Jiang, Eunhye Lee, Jieun Bae, Wonjoon Moon, Shin Hye Chung, Kyung Mi Woo

Abstract read

In one paragraph

Article in Biomaterials research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeong-Hyun RyuDepartment of Molecular Genetics, School of Dentistry, Seoul National University, Seoul, Republic of Korea.

En Shi JiangDepartment of Dental Biomaterials Science, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.

Eunhye LeeDepartment of Molecular Genetics, School of Dentistry, Seoul National University, Seoul, Republic of Korea.

Jieun BaeDepartment of Molecular Genetics, School of Dentistry, Seoul National University, Seoul, Republic of Korea.

Wonjoon MoonDepartment of Dental Biomaterials Science, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.

Shin Hye ChungDepartment of Dental Biomaterials Science, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.

Kyung Mi WooDepartment of Molecular Genetics, School of Dentistry, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-2782-1189

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While calcium silicate (CS) remains a gold standard material for vital pulp therapy, its clinical efficacy is frequently compromised by an abrupt ion release during the initial setting phase that induces extreme alkalinity and acute cytotoxicity. We engineered electrospun poly-ε-caprolactone (PCL)/CS composite fibers to reconfigure CS hydration kinetics, achieving sustained and controlled ion release. In vitro evaluation using phase-specific eluates and defined pH/Ca

Identifiers

PMID42453384

DOI10.34133/bmr.0388

PMCPMC13365599

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.