Evidence map›Paper›PMID 42453299›Full record

ArticleBiomedical reports2026

Assessment of biliary tree anatomy and its clinical implications.

Wafaa Mahmoud, Naser Obeidat, Hadeel Al-Jarrah, Ahmad Alrawashdeh, Abdulla Mohammed, Ala Abu Dalou, Saad Mahmoud

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Article in Biomedical reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Wafaa MahmoudDepartment of Anatomy, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Naser ObeidatDepartment of Diagnostic Radiology and Nuclear Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Hadeel Al-JarrahDepartment of Anatomy, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Ahmad AlrawashdehDepartment of Allied Medical Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan.
Abdulla MohammedDepartment of Diagnostic Radiology and Nuclear Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Ala Abu DalouDepartment of Diagnostic Radiology and Nuclear Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.
Saad MahmoudDepartment of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anatomical variations in the intrahepatic duct (IHD) and cystic duct (CD) are common, and their accurate identification is essential for preoperative planning. The present study aimed to assess the prevalence of biliary ductal variations using magnetic resonance cholangiopancreatography (MRCP), to explore the association between IHD and CD and to evaluate potential associations with common biliary disorders. In the present retrospective study, a total of 259 patients, who were referred for MRCP due to various biliary-related clinical indications, including biliary stones, cholecystitis and obstructive jaundice, between January 2019 and December 2023, were included. Variations of the IHD and CD were classified based on imaging findings. Associations with biliary stones, cholecystitis and obstructive jaundice were assessed using the χ² test and univariable and multivariable logistic regression analyses. IHD variations were identified in 38.6% of cases, which was most commonly attributed to a trifurcation pattern (22%), followed by drainage of the right posterior duct into the common hepatic duct (8.5%) or the left hepatic duct (7.7%). CD variations were observed in 36.7% of cases, which were most commonly medial anterior (17.8%) or posterior (18.9%) spiral insertions. A significant association was found between IHD and CD variations (P=0.010). CD variations were also associated with a higher prevalence of biliary stones (P=0.023) and cholecystitis (P=0.048). In multivariable analysis, IHD variation [adjusted odds ratio (aOR)=1.95; 95% confidence interval (CI), 1.14-3.35; P=0.015] and biliary stones (aOR=1.79; 95% CI, 1.03-3.12; P=0.041) were independent predictors of CD anatomical variants. In conclusion, anatomical variations of the IHD and CD were common and strongly associated. Recognizing these variants could be essential for preoperative planning and aid in anticipating complications, particularly given their association with stone formation and cholecystitis.

Indexed as

bile ductCDhepatic ductMRCPstones

Identifiers

PMID42453299
PMCPMC13365791

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