ArticleNeuro-oncology practice2026
Prognostic associations of steroid use in patients with glioblastoma: A population-based study.
Article in Neuro-oncology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A Permanent but Not Transient Postoperative Deficit Has Impact on OS and PFS in IDHwt-Glioma Patients.Journal of clinical medicine · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Steroids are broadly used in patients with brain tumors. A possible detrimental association of corticosteroid treatment with outcome in patients with glioblastoma has been reported but not explored on a population level. Methods: Clinical data, including corticosteroid use and related complications, of 223 patients diagnosed with isocitrate dehydrogenase wild-type glioblastoma in the years from 2010 to 2014 in the Canton of Zurich, Switzerland, were retrospectively analyzed. Survival data were estimated with the Kaplan-Meier method. Cox proportional hazards regression models were used to test the association of clinical variables with survival. Results: Most patients ( Conclusion: Steroid use at the 6-month landmark after diagnosis is independently associated with inferior survival in patients with glioblastoma. Limitations of the study include its retrospective design and the confounding factor that 1 frequent indication of steroid treatment is a symptomatic tumor. The biological mechanisms mediating this effect remain incompletely understood. Our findings support a cautious use of steroids and highlight the importance of minimizing dose and duration whenever clinically feasible.
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