ArticleFrontiers in bioengineering and biotechnology2026
Synergistic enhancement of tenogenic differentiation in adipose-derived stem cells via TGF-β and laser therapy.
Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Adipose-derived stem cells (ADSCs) are increasingly explored for tendon regeneration owing to their accessibility and multipotency. Low-level laser therapy (LLLT), also referred to as Photobiomodulation (PBM), has emerged as a promising non-invasive approach for modulating cellular behavior. However, directing their differentiation into tenocytes remains an ongoing focus of optimization. This study investigates the synergistic effects of transforming growth factor-beta (TGF-β) and PBM on the tenogenic differentiation of ADSCs. ADSCs were cultured and exposed to specific PBM wavelengths (525 nm, 825 nm, and consecutive irradiation) at 5 and 10 J/cm
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