ArticleFEBS open bio2026
Optimizing photoexcitation conditions for time-resolved X-ray solution scattering experiments.
Article in FEBS open bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Investigating the dynamics of biological molecules in real time is crucial to understand their biological function. Time-resolved X-ray solution scattering (TR-XSS) is an experimental technique that allows one to follow large-scale conformational changes of biological molecules in solution induced by a triggering event. In many cases, the triggering event is the absorption of a laser pulse, either by the biological molecule of interest or by photocaged compounds present in solution. Selecting the optimal photoexcitation conditions is a critical step in a TR-XSS experiment and it requires taking into account the laser beam properties, the sample characteristics, and the photoexcitation geometry. This protocol describes how to select the accessible experimental parameters in order to maximize the TR-XSS signal while avoiding nonlinear effects induced by an excessive laser peak power density. The provided set of guidelines will aid the experimentalists in the preparation and realization of their TR-XSS experiments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.