ArticlePlants (Basel, Switzerland)2026
Comprehensive Candidate Gene for Ginsenoside Rg1 Biosynthesis: Identification, Systematic Analysis, and Verification.
Article in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Ginsenoside Rg1 has a broad spectrum of pharmacological activities, and its concentration is a key indicator of ginseng quality. Because ginsenoside levels are quantitative traits controlled by multiple genes and environmental factors, identifying genes involved in Rg1 biosynthesis is essential to improve its production in ginseng. Transcriptome analysis of 344 4-year-old ginseng roots identified 33 Candidate Genes implicated in Rg1 biosynthesis. These candidates were detected through differential expression analysis, SNP/InDel mutation screening, correlation analysis with Rg1 content variation, and co-expression network analysis. By integrating GO functional annotation, gene expression profiles, and Rg1 content correlations, a putative biosynthetic pathway for Rg1 was inferred and the roles of these genes were preliminarily clarified. Further study of MeJA regulation confirmed that
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