Evidence map›Paper›PMID 42452083›Full record

ArticlePolymers2026

Development of Polylactic Acid-Curcumin Composite Films with Dual-Metal-Doped Copper Oxide Nanoparticles for Sustainable Antioxidant, Biocompatible, Photothermal, and Antibacterial Performance.

Gopinath Kasi, Sarinthip Thanakkasaranee, Nattan Stalin, Tae-Sik Park, Ramar Dharmaraj, Kittisak Jantanasakulwong, Nuttapol Tanadchangsaeng, Pornchai Rachtanapun

Abstract read
In one paragraph

Article in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gopinath KasiDivision of Packaging Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.ORCID 0000-0002-5811-2668
Sarinthip ThanakkasaraneeDivision of Packaging Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.ORCID 0000-0003-2520-4854
Nattan StalinDepartment of Life Science, Gachon University, Seongnam 13120, Republic of Korea.ORCID 0000-0001-8273-0362
Tae-Sik ParkDepartment of Life Science, Gachon University, Seongnam 13120, Republic of Korea.
Ramar DharmarajDepartment of Botany, Alagappa University, Karaikudi 630003, Tamil Nadu, India.ORCID 0009-0000-5297-6687
Kittisak JantanasakulwongDivision of Packaging Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.
Nuttapol TanadchangsaengCollege of Biomedical Engineering, Rangsit University, Lak-Hok, Pathumthani 12000, Thailand.ORCID 0000-0002-2871-8159
Pornchai RachtanapunDivision of Packaging Technology, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.ORCID 0000-0001-8157-4433

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polylactic acid (PLA)-curcumin (CCM) composites, incorporating various contents of surface-functionalized dual-metal-doped copper oxide (SF-M-CuO), were prepared by the solution casting method. Synthesized composite films were evaluated for their antioxidant, biocompatible, photothermal, and antibacterial properties. The 4% CCM exhibits excellent compatibility based on total color difference, antioxidant activity, and controlled curcumin release behavior. In addition, different contents of SF-M-CuO (1-4%) were added to the PLA-4%-CCM polymer matrix. Synthesized composite films were characterized through functional, structural, and topographical analyses. FTIR and XRD analyses confirmed the successful incorporation of CCM and SF-M-CuO into the PLA matrix, which enhanced interfacial interactions and increased the crystallinity index by acting as effective nucleating agents. ABTS and DPPH radical scavenging assays revealed dose-dependent antioxidant activity due to the synergistic effects of CCM and SF-M-CuO. Biocompatibility evaluation using RAW 264.7 macrophage cells demonstrated non-toxic responses and enhanced cell proliferation in PLA-4%-CCM composite films containing up to 3%-SF-M-CuO. Among the fabricated films, PLA-4%-CCM-3%-SF-M-CuO exhibited superior photothermal performance and excellent antibacterial activity against

Indexed as

active food packagingbiocompatibilitycopper oxide nanoparticlescurcuminnucleating agentspolylactic acidsustainable material innovationsynergistic effects

Identifiers

PMID42452083
PMCPMC13364498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.