Evidence map›Paper›PMID 42452067›Full record

ArticlePolymers2026

Comparison of EDC/NHS and Pentasodium Triphosphate (TPP) as Cross-Linking Agents for Nanohydroxyapatite, Silk Fibroin, and Chitosan 3D Scaffolds.

Anna Tuwalska, Alina Sionkowska, Grzegorz Tylko, Maciej Przybyłek, Anna Maria Osyczka, Iwona Białas, Michele Laus

Abstract read
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In one paragraph

Article in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna TuwalskaDepartment of Biomaterials and Cosmetics Chemistry, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, 87-100 Toruń, Poland.ORCID 0000-0002-1589-3169
Alina SionkowskaDepartment of Biomaterials and Cosmetics Chemistry, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, 87-100 Toruń, Poland.ORCID 0000-0002-1551-2725
Grzegorz TylkoDepartment of Biology and Cell Imaging, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.ORCID 0000-0002-6669-0142
Maciej PrzybyłekInstitute of Advanced Studies, Nicolaus Copernicus University in Toruń, Wileńska 4, 87-100 Toruń, Poland.ORCID 0000-0002-3399-6129
Anna Maria OsyczkaDepartment of Biology and Cell Imaging, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, 30-387 Kraków, Poland.
Iwona BiałasCosmetoSAFE Consulting LLC, 05-500 Piaseczno, Poland.ORCID 0000-0003-2605-6013
Michele LausDepartment of Science and Technological Innovation, University of Eastern Piedmont "A. Avogadro", 15121 Alessandria, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study compares two scaffold cross-linking strategies, EDC/NHS and pentasodium triphosphate (TPP), applied to nanohydroxyapatite/silk fibroin/chitosan (nHA/SF/CTS) scaffolds. The effects of the cross-linking strategy on scaffold morphology, ATR-FTIR profile, swelling, in vitro degradation, and compressive properties were evaluated. In addition, the biological response of selected 20:40:40 and 15:70:15 (

Indexed as

cellular responseschitosancross-linking agentsnanohydroxyapatitepore size and shapescaffoldssilk fibrointoxicity

Identifiers

PMID42452067
PMCPMC13364012

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.