ReviewMaterials (Basel, Switzerland)2026
Applications of Nanomaterials in Restorative Dentistry and Endodontics: A Narrative Review.
Review in Materials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- LL-37-based oral antimicrobial therapeutics: translational challenges and future directions-a narrative review.Odontology · 2026Review
- Cariogenic Risk Modifies the Effect of Marginal Adaptation on Caries Adjacent to Posterior Composite Restorations: A Stratified Multivariate Analysis.Clinics and practice · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanotechnology has emerged as a promising strategy in restorative dentistry and endodontics due to the physicochemical and biological properties of nanomaterials. This narrative review aimed to critically analyze the current applications of nanomaterials in restorative dentistry and endodontics, highlighting their mechanisms of action, biological properties, and translational potential. A literature search was performed in the PubMed/MEDLINE database using combinations of MeSH terms and free keywords related to nanomaterials and dental applications. Studies published in English within the last twenty years and addressing restorative or endodontic applications were considered. After screening and eligibility assessment, 69 studies were included in the descriptive analysis. The findings indicate that nanomaterials have been investigated in preventive strategies, adhesive systems, restorative materials, intracanal medicaments, endodontic sealers, vital pulp therapy, and regenerative formulations. In restorative dentistry, nanoparticles such as silver nanoparticles, nano-hydroxyapatite, amorphous calcium phosphate, bioactive glass nanoparticles, and chitosan-based systems showed favorable antimicrobial, remineralizing, and material-enhancing properties. In endodontics, silver and chitosan nanoparticles showed potential for intracanal disinfection and biofilm disruption, while chlorhexidine, zinc, and bioactive glass nanoparticles enhanced the antimicrobial activity and sealing ability of endodontic sealers. In addition, magnetic nanoparticles, mesoporous silica nanoparticles, and hydroxyapatite nanoparticles presented promising applications in regenerative endodontics and vital pulp therapy. However, most of the available evidence is still based on in vitro studies, with limited long-term clinical validation. Overall, nanotechnology offers potential experimental advantages for improving preventive, restorative, and endodontic therapies; however, its successful clinical translation remains strictly dependent on overcoming critical biosafety barriers and addressing long-term toxicity concerns.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.