Evidence map›Paper›PMID 42451745›Full record

ArticleMolecules (Basel, Switzerland)2026

Integrated Chemical, In Silico, and Functional Neurobehavioral Evaluation of Three Essential Oils in Acute Anxiety- and Depression-Related Mouse Models.

Marilú Roxana Soto-Vásquez, Paul Alan Arkin Alvarado-García, Demetrio Rafael Jara-Aguilar, José Gilberto Gavidia-Valencia, Segundo Guillermo Ruiz-Reyes, Roger Antonio Rengifo-Penadillos

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marilú Roxana Soto-VásquezGrupo de Investigación en Productos Naturales y Sustancias Bioactivas, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, Av. Juan Pablo II s/n, Trujillo 13011, Peru.ORCID 0000-0002-1178-4678
Paul Alan Arkin Alvarado-GarcíaFacultad de Ciencias de la Salud, Universidad Autónoma del Perú, Panamericana Sur Km. 16.3, Villa EI Salvador, Lima 15801, Peru.ORCID 0000-0003-1641-207X
Demetrio Rafael Jara-AguilarGrupo de Investigación en Productos Naturales y Sustancias Bioactivas, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, Av. Juan Pablo II s/n, Trujillo 13011, Peru.
José Gilberto Gavidia-ValenciaGrupo de Investigación en Productos Naturales y Sustancias Bioactivas, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, Av. Juan Pablo II s/n, Trujillo 13011, Peru.
Segundo Guillermo Ruiz-ReyesGrupo de Investigación en Productos Naturales y Sustancias Bioactivas, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, Av. Juan Pablo II s/n, Trujillo 13011, Peru.ORCID 0000-0003-1368-8409
Roger Antonio Rengifo-PenadillosGrupo de Investigación en Productos Naturales y Sustancias Bioactivas, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, Av. Juan Pablo II s/n, Trujillo 13011, Peru.ORCID 0000-0002-9019-3744

Funding

PROCIENCIA-CONCYTEC (PERÚ) PE501087339-2024-PROCIENCIA
6 · The paper itself

Abstract

Essential oils are multicomponent natural products with potential neurobehavioral activity, but integrated comparative studies remain limited. This study compared the essential oils of

Indexed as

Anti-Anxiety AgentsAnxietyBehavior, AnimalDepressionOils, VolatileAnimalsAntidepressive AgentsComputer SimulationDisease Models, AnimalFlumazenilMaleMiceMice, Inbred BALB CMolecular Docking SimulationPiperazinesPyridinesAnti-Anxiety AgentsAntidepressive AgentsFlumazenilN-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamideOils, VolatilePiperazinesPyridinesantidepressant-like activityanxiolytic-like activitycorticosteroneessential oilsflumazenilmolecular dockingPeperomia dolabriformisRosmarinus officinalisSatureja brevicalyxWAY-100635

Identifiers

PMID42451745
PMCPMC13362989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.