Evidence map›Paper›PMID 42451718›Full record

ArticleMolecules (Basel, Switzerland)2026

Subcritical Water Extraction Enables the Production of Cichoric and Caftaric Acid-Standardized

Petko Denev, Desislava Teneva, Manol Ognyanov, Mariya Pimpilova, Ani Petrova, Georgi Dimitrov, Bela Vasileva, Kamelia Hristova-Panusheva, Natalia Krasteva, George Miloshev and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Petko DenevLaboratory of Biologically Active Substances, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-2290-791X
Desislava TenevaLaboratory of Biologically Active Substances, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 4000 Plovdiv, Bulgaria.ORCID 0000-0003-3109-2238
Manol OgnyanovLaboratory of Biologically Active Substances, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-5568-0854
Mariya PimpilovaLaboratory of Biologically Active Substances, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 4000 Plovdiv, Bulgaria.ORCID 0000-0002-6105-2715
Ani PetrovaLaboratory of Biologically Active Substances, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 4000 Plovdiv, Bulgaria.
Georgi DimitrovLaboratory of Biologically Active Substances, Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 4000 Plovdiv, Bulgaria.
Bela VasilevaInstitute of Molecular Biology "Acad. R. Tsanev", Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0002-8718-6412
Kamelia Hristova-PanushevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-8348-8336
Natalia KrastevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-7423-7412
George MiloshevInstitute of Molecular Biology "Acad. R. Tsanev", Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0003-2979-8899
Milena GeorgievaInstitute of Molecular Biology "Acad. R. Tsanev", Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0002-2371-7544

Funding

European Union BG-RRP-2.017-0043/16.12.2024European Union through the NextGenerationEU instrument BG-RRP-2.017-0043/16.12.2024
6 · The paper itself

Abstract

This study investigates subcritical water extraction (SWE) as an alternative to hydroalcoholic extraction for the production of

Indexed as

Caffeic AcidsCoumaric AcidsEchinaceaPlant ExtractsPlant RootsSuccinatesWaterHumansPhenolsTemperatureCaffeic Acidscaftaric acidchicoric acidCoumaric AcidsPhenolsPlant ExtractsSuccinatesWaterEchinacea purpurea rootextract standardizationhydroxycinnamic acids thermal decompositionplant cell wall degradationsubcritical water extraction

Identifiers

PMID42451718
PMCPMC13362611

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.