Evidence map›Paper›PMID 42451711›Full record

ArticleMolecules (Basel, Switzerland)2026

Fluorophenylalanine-Containing Dipeptides with Antibiofilm Activity Against

Amy B Dounay, Amelia A Fuller, Dylan R Y Lawton, Sarah Buchman, Markus F Bergstrom, Rose Gilmore, Emerson Hernly, Jake Hitchens, Justin Tee, Callista Tran and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Amy B DounayDepartment of Chemistry and Biochemistry, Colorado College, 14 E. Cache La Poudre Street, Colorado Springs, CO 80903, USA.ORCID 0000-0003-0451-5549
Amelia A FullerDepartment of Chemistry and Biochemistry, Santa Clara University, 500 El Camino Real, Santa Clara, CA 95053, USA.ORCID 0000-0002-9291-6037
Dylan R Y LawtonDepartment of Chemistry and Biochemistry, Santa Clara University, 500 El Camino Real, Santa Clara, CA 95053, USA.ORCID 0000-0002-5415-4123
Sarah BuchmanDepartment of Molecular Biology, Colorado College, 14 E. Cache La Poudre Street, Colorado Springs, CO 80903, USA.
Markus F BergstromDepartment of Chemistry and Biochemistry, Colorado College, 14 E. Cache La Poudre Street, Colorado Springs, CO 80903, USA.ORCID 0000-0003-2194-7618
Rose GilmoreDepartment of Biology, Indiana University Indianapolis, 723 W. Michigan Street, SL 330, Indianapolis, IN 46202, USA.
Emerson HernlyDepartment of Chemistry and Chemical Biology, Indiana University Indianapolis, 402 N. Blackford St., LD 326, Indianapolis, IN 46202, USA.
Jake HitchensDepartment of Chemistry and Chemical Biology, Indiana University Indianapolis, 402 N. Blackford St., LD 326, Indianapolis, IN 46202, USA.
Justin TeeDepartment of Chemistry and Biochemistry, Colorado College, 14 E. Cache La Poudre Street, Colorado Springs, CO 80903, USA.
Callista TranDepartment of Chemistry and Biochemistry, Colorado College, 14 E. Cache La Poudre Street, Colorado Springs, CO 80903, USA.
Nathan WeilerDepartment of Biology, Indiana University Indianapolis, 723 W. Michigan Street, SL 330, Indianapolis, IN 46202, USA.
Gregory G AndersonDepartment of Biology, Indiana University Indianapolis, 723 W. Michigan Street, SL 330, Indianapolis, IN 46202, USA.
Olivia HattonDepartment of Molecular Biology, Colorado College, 14 E. Cache La Poudre Street, Colorado Springs, CO 80903, USA.
Kathleen A MarrsDepartment of Biology, Indiana University Indianapolis, 723 W. Michigan Street, SL 330, Indianapolis, IN 46202, USA.ORCID 0009-0009-6904-7767
Kristen MudrackDepartment of Chemistry, Milligan University, 1 Blowers Boulevard, Milligan, TN 37682, USA.
Martin J O'DonnellDepartment of Chemistry and Chemical Biology, Indiana University Indianapolis, 402 N. Blackford St., LD 326, Indianapolis, IN 46202, USA.
Doug SchirchDepartment of Chemistry, Goshen College, 1700 South Main Street, Goshen, IN 46526, USA.
Kevin SullivanDepartment of Chemistry, University of Indianapolis, 1400 East Hanna Avenue, Indianapolis, IN 46227, USA.
J Geno SamaritoniDepartment of Chemistry and Chemical Biology, Indiana University Indianapolis, 402 N. Blackford St., LD 326, Indianapolis, IN 46202, USA.
William L ScottDepartment of Chemistry and Chemical Biology, Indiana University Indianapolis, 402 N. Blackford St., LD 326, Indianapolis, IN 46202, USA.

Funding

Camille and Henry Dreyfus Foundation 2017National Science Foundation CHE-1566604
6 · The paper itself

Abstract

Discovery of new antibiotic candidates is driven by urgent global health needs and evolving resistance to current treatments. In pursuit of novel peptide-based antibiotics, more than 100 dipeptides containing fluorinated phenylalanine (F-Phe) residues were synthesized by undergraduate researchers at eight institutions and evaluated against

Indexed as

Anti-Bacterial AgentsBiofilmsDipeptidesPhenylalaninePseudomonas aeruginosaHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsDipeptidesPhenylalanineantimicrobial peptidesbioactive peptidesphenotypic screeningprodrugselective toxicitysolid-phase peptide synthesis

Identifiers

PMID42451711
PMCPMC13363317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.