Disulfide-Crosslinked mPEG-PLA-(LA)

Yukun Xie, Hao Wang, Lanlan Xiang, Yuchen Shen, Yujie Yang, Jiajie Liu, Xin Teng

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yukun XieShanghai Key Laboratory of Advanced Polymeric Materials, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.

Hao WangShanghai Key Laboratory of Advanced Polymeric Materials, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.

Lanlan XiangShanghai Key Laboratory of Advanced Polymeric Materials, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.

Yuchen ShenFaculty of Biomedical Engineering, University of New South Wales, Sydney, NSW 2052, Australia.

Yujie YangShanghai Key Laboratory of Advanced Polymeric Materials, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.

Jiajie LiuShanghai Key Laboratory of Advanced Polymeric Materials, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.

Xin TengShanghai Key Laboratory of Advanced Polymeric Materials, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.ORCID 0000-0001-5712-3202

Funding

Shanghai Natural Science Foundation 25ZR1401086

6 · The paper itself

Abstract

Taxanes represent a crucial class of chemotherapeutic agents clinically employed for the treatment of various malignancies, including breast cancer. Three commonly utilized taxanes-paclitaxel (Taxol), docetaxel (Taxotere), and cabazitaxel-are substantially limited by inherent drawbacks such as poor aqueous solubility, rapid clearance, and non-specific distribution. To enhance their anti-tumor efficacy against breast cancer, an mPEG-PLA-(LA)

Indexed as

Antineoplastic AgentsBreast NeoplasmsDisulfidesDrug CarriersMicellesNanoparticlesPolyestersPolyethylene GlycolsTaxoidsAnimalsCell Line, TumorDocetaxelDrug Delivery SystemsFemaleHumansMCF-7 CellsAntineoplastic AgentscabazitaxelDisulfidesDocetaxelDrug Carriersmethoxy poly(ethylene glycol)-poly(lactide)MicellesPaclitaxelPolyestersPolyethylene GlycolsTaxoidsbreast cancercabazitaxeldisulfide-crosslinkeddocetaxelnanomicellespaclitaxel

Identifiers

PMID42451609

DOI10.3390/molecules31132238

PMCPMC13363478

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.