Evidence map›Paper›PMID 42451163›Full record

ArticleNutrients2026

Applying Implementation Science to Secure a Sustainable Supply of UNIMMAP MMS for National Antenatal Care Services in Indonesia.

Holis Abdul Holik, Otte Santika, Auliya Suwantika, John Atwater, Jarno de Lange, Abdul Razak Thaha, Endang Laksminingsih Achadi, Hera Nurlita, Erni Rahmawati, Rimbawan and 1 more

Abstract read
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Holis Abdul HolikCenter of Excellence for Pharmaceutical Care Innovation (PHARCI), Faculty of Pharmacy, Padjadjaran University, Jl. Ir Soekarno KM 21, Jatinangor Sub-District, Sumedang Regency 45363, West Java Province, Indonesia.ORCID 0000-0002-1303-8812
Otte SantikaThe Vitamin Angel Alliance, Indonesia, Ruko Sentul Tower Apartment (STA) Niaga Blok B No. 2, Citaringgul, Babakan Madang, Bogor Regency 16810, West Java Province, Indonesia.
Auliya SuwantikaCenter of Excellence for Pharmaceutical Care Innovation (PHARCI), Faculty of Pharmacy, Padjadjaran University, Jl. Ir Soekarno KM 21, Jatinangor Sub-District, Sumedang Regency 45363, West Java Province, Indonesia.ORCID 0000-0001-8671-2065
John AtwaterAtaqua Regulatory Services, 20878 Blue Ridge Mountain Road, Paris, VA 20130, USA.
Jarno de LangeThe Vitamin Angel Alliance, 6500 Hollister Ave Suite 130, Goleta, CA 93117, USA.
Abdul Razak ThahaIndonesian MMS-TAG, Indonesian Nutrition Initiative (IGI), Kompleks Bappenas A1 Jl. Siaga Raya Pejaten, Jakarta Selatan City 12510, Jakarta Province, Indonesia.
Endang Laksminingsih AchadiCenter for Family Welfare Research (PUSKA), Faculty of Public Health, Universitas Indonesia, Building G No. 210, Depok City 16424, West Java Province, Indonesia.
Hera NurlitaDirectorate of Family Health Service, Ministry of Health, H.R. Rasuna Said Road Blok X-5 Kavling 4-9, Jakarta Selatan City 12950, Jakarta Province, Indonesia.
Erni RahmawatiDirectorate of Traditional Medicine, Health Supplement and Cosmetic Standardization, The Indonesian Food and Drug Authority of The Republic of Indonesia (BPOM), Bhinneka Tunggal Ika Building, 2nd Floor, Jl. Percetakan Negara No. 23, Jakarta 10560, Jakarta Province, Indonesia.
RimbawanDepartment of Community Nutrition, Faculty of Human Ecology, IPB University, FEMA Building W1-L2, Jl. Kamper, IPB Dramaga Campus, Bogor Regency 16680, West Java Province, Indonesia.ORCID 0000-0002-2421-5933
Clayton AjelloKirk Humanitarian, 2755 E. Cottonwood Parkway, Suite 450, Salt Lake City, UT 84121, USA.ORCID 0009-0007-7462-9548

Funding

Kirk Humanitarian 1-0219Ministry of Health Republic of Indonesai (in-kind support) no defined grant numberThe Vitamin Angel Alliance no defined number
6 · The paper itself

Abstract

backgroundThe United Nations International Multiple Micronutrient Antenatal Preparation of a multiple micronutrient supplement (UNIMMAP MMS or MMS) is replacing iron and folic acid supplementation (IFAS) in antenatal care (ANC) in low- and middle-income countries (LMICs). An investigation into determining how to secure a sustainable supply of MMS began in response to the Indonesian Ministry of Health (MOH)'s decision to introduce MMS into its national health services.

objectiveWe aimed to identify and test sustainable strategies for securing MMS supplies.

methodsA three-phase implementation science framework was applied to (1) foster an enabling environment for securing MMS supplies, (2) undertake implementation research (IR) to compare sourcing strategy options, and (3) plan and execute actions to scale MMS supply availability and distribution. The MOH assumed ownership of the initiative and guided policy, procurement, and program decisions.

results(1) Landscaping resulted in recommendations that triggered supply-related policies, an accommodating regulatory framework, integration of MMS into key government support systems (i.e., budget, finance, procurement, and distribution), and identification of supply strategy options. (2) IR resulted in the selection of a local manufacturing and sourcing strategy for acquiring a sustainable supply of high-quality MMS product while retaining an option to import a limited supply of MMS during scaling. (3) A multi-year plan was developed to scale MMSs within ANC services.

conclusionsApplying implementation science provided an evidence-based framework with which to identify, establish, and test a sustainable strategy for securing MMS supplies and yielded insights useful for other countries introducing MMS into their national health systems.

Indexed as

Dietary SupplementsImplementation ScienceMicronutrientsPrenatal CareFemaleHumansIndonesiaPregnancyUnited NationsMicronutrientsexpert consensus specificationimplementation researchimplementation sciencemanufacturingMMSsecuring a sustainable supply of MMSUNIMMAP

Identifiers

PMID42451163
PMCPMC13363487

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.