Evidence map›Paper›PMID 42451157›Full record

ReviewNutrients2026

Milk Intake, Sun Exposure, and Caffeinated Energy Drink Consumption in Children and Adolescents: Evidence, Uncertainty, and Implications for Peak Bone Mass Accrual.

Giorgos K Sakkas, Ilias Ntoumas, Antonis Tsagkalis, Christina Karatzaferi

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giorgos K SakkasDepartment of Physical Education and Sport Science, University of Thessaly, GR42100 Thessaly, Greece.ORCID 0000-0002-2462-995X
Ilias NtoumasDepartment of Physical Education and Sport Science, University of Thessaly, GR42100 Thessaly, Greece.ORCID 0000-0001-6270-8782
Antonis TsagkalisDepartment of Physical Education and Sport Science, University of Thessaly, GR42100 Thessaly, Greece.
Christina KaratzaferiDepartment of Physical Education and Sport Science, University of Thessaly, GR42100 Thessaly, Greece.ORCID 0000-0002-8266-5780

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesChildhood and adolescence are critical periods for bone mineral accrual and future skeletal reserve. Milk intake, sun exposure and caffeinated energy drink consumption are familiar lifestyle concepts, but they differ substantially in biological proximity and evidential strength. This structured narrative review critically evaluates these exposures in relation to peak bone mass accrual in youth.

methodsPubMed/MEDLINE, Scopus, Web of Science, the Cochrane Library and Google Scholar were searched from database inception to 23 June 2026. Search terms combined pediatric population terms with bone outcomes and exposure terms related to milk/dairy, calcium, vitamin D, sun exposure, physical activity, sleep, caffeine and energy drinks. A literature collection flowchart and a GRADE-informed evidence appraisal table are provided to improve transparency and clinical interpretability.

resultsEvidence is strongest for adequate calcium intake, calcium-rich foods and weight-bearing physical activity as modifiable contributors to skeletal accrual. Vitamin D is essential for mineral homeostasis, but supplementation effects on bone density in otherwise healthy children are context-dependent and appear most relevant for deficiency prevention or treatment. Milk intake is best interpreted as a practical marker of calcium-rich dietary patterns rather than as the only route to calcium adequacy. Sun exposure is an indirect determinant of vitamin D status and is modified by season, latitude, skin pigmentation, clothing, sunscreen, adiposity and outdoor behavior. Direct evidence linking caffeinated energy drinks to impaired pediatric bone accrual is very limited. The relevance of caffeinated energy drink intake is better framed as indirect and hypothesis-generating, through possible displacement of calcium-rich beverages, sleep disruption and clustering with poorer lifestyle patterns.

conclusionsA prevention framework for pediatric bone health should emphasize calcium adequacy, avoidance of vitamin D deficiency, mechanical loading and correct pediatric DXA interpretation using Z-scores. Energy drinks can be included as a lifestyle concern, but conclusions should remain cautious because direct skeletal evidence is limited.

Indexed as

Bone DensityCaffeineEnergy DrinksMilkSunlightAdolescentAnimalsCalcium, DietaryChildExerciseHumansVitamin DCaffeineCalcium, DietaryVitamin Dadolescentsbone mineral densitycaffeinecalciumchildrendairyDXAenergy drinksGRADEmilkpeak bone massphysical activitysleepsun exposurevitamin DZ-score

Identifiers

PMID42451157
PMCPMC13363486

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.