Evidence map›Paper›PMID 42451133›Full record

ArticleNutrients2026

Comparative Bioassay-Guided Fractionation of

Noha Swilam, Khaled A Nematallah, Amgad Albohy, Noha M Badawi, Sameh S Gad, Maha M Shouman, Saeed S Al-Ghamdi, Abdullah R Alzahrani, Nahla Ayoub

Abstract readComparative Study
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Noha SwilamDepartment of Pharmacognosy, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo 11837, Egypt.ORCID 0000-0003-1846-2265
Khaled A NematallahDepartment of Pharmacognosy, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo 11837, Egypt.
Amgad AlbohyDepartment of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0003-3021-8767
Noha M BadawiDepartment of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo 11837, Egypt.ORCID 0000-0002-3823-5804
Sameh S GadDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, October University for Modern Sciences, and Arts MSA, 6th October City 12451, Egypt.ORCID 0000-0002-1876-0548
Maha M ShoumanDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, October University for Modern Sciences, and Arts MSA, 6th October City 12451, Egypt.ORCID 0000-0003-1254-2504
Saeed S Al-GhamdiDepartment of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah 24382, Saudi Arabia.
Abdullah R AlzahraniDepartment of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah 24382, Saudi Arabia.ORCID 0000-0001-7782-0574
Nahla AyoubDepartment of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah 24382, Saudi Arabia.ORCID 0000-0003-4490-889X

Funding

Umm al-Qura University 26UQU4350639GSSR01
6 · The paper itself

Abstract

backgroundSkin aging is driven by oxidative stress and ultraviolet (UV) exposure, leading to extracellular matrix degradation and loss of skin elasticity. This study aimed to identify the most biologically active

methodsHydroalcohol extracts and ethyl acetate fractions of

resultsThe ethyl acetate fraction of

conclusionsThe polyphenol-rich leaf fraction from

Indexed as

CitrusPhytochemicalsPlant ExtractsPlant LeavesPolyphenolsSkin AgingAnimalsAntioxidantsBiological AssayFibroblastsHumansMiceOxidative StressPancreatic ElastaseSkinTandem Mass SpectrometryAntioxidantsPancreatic ElastasePhytochemicalsPlant ExtractsPolyphenolsanti-aging enzymeantioxidant activityCitrus aurantifoliaLC–MS/MSmolecular dynamicsnanovesicleswound-healing

Identifiers

PMID42451133
PMCPMC13364407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.