Evidence map›Paper›PMID 42451089›Full record

Trial reportNutrients2026

Effects of Probiotic-Phytonutrient Blends on Defecation, Intestinal Barrier Function, and Gut Microbiota: A Randomized, Placebo-Controlled Trial.

Ah Young Hwang, Sunyoung Lee, JungHyun Yoon, Kyu Yeon Lee, Dong Ho Suh, Sungjae Myung, Jihye Song, Hae Jo, Dmitri Sitnikov, Jong Hoon Won and 6 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ah Young HwangHEM PHARMA Inc., Suwon 16229, Republic of Korea.
Sunyoung LeeHEM PHARMA Inc., Suwon 16229, Republic of Korea.ORCID 0009-0003-3207-2308
JungHyun YoonHEM PHARMA Inc., Suwon 16229, Republic of Korea.
Kyu Yeon LeeHEM PHARMA Inc., Suwon 16229, Republic of Korea.
Dong Ho SuhHEM PHARMA Inc., Suwon 16229, Republic of Korea.
Sungjae MyungHEM PHARMA Inc., Suwon 16229, Republic of Korea.
Jihye SongAmway Research and Development, Ada, MI 49355, USA.
Hae JoAmway Research and Development, Ada, MI 49355, USA.
Dmitri SitnikovAmway Research and Development, Ada, MI 49355, USA.
Jong Hoon WonAmway Research and Development, Ada, MI 49355, USA.
Hyun Young ParkAmway Research and Development, Ada, MI 49355, USA.
Matthew K RunyonAmway Research and Development, Ada, MI 49355, USA.
Donghyun ChoHEM PHARMA Inc., Suwon 16229, Republic of Korea.
Wilhelm H HolzapfelHEM PHARMA Inc., Suwon 16229, Republic of Korea.ORCID 0000-0002-3669-1419
Yosep JiHEM PHARMA Inc., Suwon 16229, Republic of Korea.
Eun Sung JungHEM PHARMA Inc., Suwon 16229, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DefecationGastrointestinal MicrobiomeIntestinal Barrier FunctionProbioticsAdultBifidobacteriumDouble-Blind MethodFatty Acids, VolatileFecesFemaleHaptoglobinsHumansLactobacillusMaleMiddle AgedProtein PrecursorsFatty Acids, VolatileHaptoglobinsProtein PrecursorsTryptophanzonulinbutyrategut microbiomeintestinal barrier functionphytonutrientsprobioticSCFAstryptophan

Identifiers

PMID42451089
PMCPMC13363449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.