Evidence map›Paper›PMID 42450786›Full record

ArticleAnimals : an open access journal from MDPI2026

"Beyond the Sad Eyes": A Pilot Study on Behavioural and Physiological Indicators in Shelter Dogs Exhibiting Depression-like Behaviour.

Sara Boero, Clara Palestrini, Greta V Berteselli, Alice Garegnani, Tanja Peric, Isabella Pividori, Alberto Prandi, Michela Minero, Silvia M Mazzola, Simona Cannas

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sara BoeroDepartment of Veterinary Medicine and Animal Science, University of Milan, Via dell'Università 6, 26900 Lodi, LO, Italy.
Clara PalestriniDepartment of Veterinary Medicine and Animal Science, University of Milan, Via dell'Università 6, 26900 Lodi, LO, Italy.ORCID 0000-0002-5178-906X
Greta V BerteselliDepartment of Veterinary Medicine and Animal Science, University of Milan, Via dell'Università 6, 26900 Lodi, LO, Italy.ORCID 0000-0002-2896-3971
Alice GaregnaniDepartment of Veterinary Medicine and Animal Science, University of Milan, Via dell'Università 6, 26900 Lodi, LO, Italy.ORCID 0009-0000-9242-8407
Tanja PericDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Via Sondrio 2B, 33100 Udine, UD, Italy.ORCID 0000-0002-5154-4222
Isabella PividoriDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Via Sondrio 2B, 33100 Udine, UD, Italy.ORCID 0000-0003-2972-7804
Alberto PrandiDepartment of Agricultural, Food, Environmental and Animal Sciences, University of Udine, Via Sondrio 2B, 33100 Udine, UD, Italy.
Michela MineroDepartment of Veterinary Medicine and Animal Science, University of Milan, Via dell'Università 6, 26900 Lodi, LO, Italy.ORCID 0000-0001-8285-5501
Silvia M MazzolaDepartment of Veterinary Medicine and Animal Science, University of Milan, Via dell'Università 6, 26900 Lodi, LO, Italy.ORCID 0000-0001-8131-4340
Simona CannasDepartment of Veterinary Medicine and Animal Science, University of Milan, Via dell'Università 6, 26900 Lodi, LO, Italy.ORCID 0000-0002-5665-7971

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shelter dogs may experience long-term environmental and social stressors that can affect their behaviour and welfare. Some individuals show reduced activity, low responsiveness to environmental stimuli, and limited interaction with their surroundings. This pilot study investigated behavioural patterns and allopregnanolone concentrations in shelter dogs exhibiting these behavioural characteristics. Ten shelter dogs were enrolled and divided into two groups: five dogs showing depression-like patterns and five matched control dogs. Each dog wore a three-axis accelerometer for 30 days to quantify activity levels. Behavioural observations were conducted using video recordings, and hair samples were collected at baseline and after 30 days to assess allopregnanolone concentrations as a potential stress marker. Dogs in the case group showed significantly longer resting time than controls (

Indexed as

accelerometryallopregnanoloneanimal welfaredepression-like patternshairinactivitystress biomarkers

Identifiers

PMID42450786
PMCPMC13359796

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.