Evidence map›Paper›PMID 42450601›Full record

ReviewBiology2026

Programmable Metal-Organic Framework Biointerfaces Against Pathogens.

Jiewen Hou, Xinzhe Song, Kaiyang Zhang, Xuehao Huo, Xinhao Sun, Kerun Zhang, Ning Wen, Di Liu, Liwei Chen, Chuncheng Xu and 4 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiewen HouCollege of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan 250200, China.
Xinzhe SongCollege of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan 250200, China.
Kaiyang ZhangCollege of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan 250200, China.
Xuehao HuoCollege of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan 250200, China.
Xinhao SunCollege of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan 250200, China.
Kerun ZhangCollege of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan 250200, China.
Ning WenShandong Provincial Key Laboratory of Green and Intelligent Building Materials, University of Jinan, Jinan 250022, China.
Di LiuDepartment of Pharmaceutical Engineering, School of Life and Health Sciences, Huzhou College, Huzhou 313000, China.
Liwei ChenCollege of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan 250200, China.ORCID 0000-0002-1929-9351
Chuncheng XuCollege of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan 250200, China.
Yen Leng PakCollege of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan 250200, China.
Zhenbin GuoAdvanced Technology Research Institute, Beijing Institute of Technology, Jinan 250300, China.
Huizi HuangAdvanced Technology Research Institute, Beijing Institute of Technology, Jinan 250300, China.ORCID 0000-0001-7309-5539
Ruodan HanAdvanced Technology Research Institute, Beijing Institute of Technology, Jinan 250300, China.

Funding

National Natural Science Foundation of China Nos. 82202240Research Program of Qilu Institute of Technology No. QIT23TP011the Shandong Provincial Natural Science Foundation Nos. ZR2024QB122the Shandong Provincial Natural Science Foundation Nos. ZR2024QE448
6 · The paper itself

Abstract

Emerging viral diseases continue to pose major challenges to global health, creating demand for materials that can support pathogen control, diagnosis, and therapy. Owing to their tunable structures and versatile biointerfaces, metal-organic frameworks (MOFs) have attracted increasing attention in anti-pathogen applications. While previous studies have often focused on individual functions such as catalysis, biosensing, or drug delivery, a broader perspective on the functional development of MOF-based systems remains limited. In this Review, we summarize recent advances in MOF-enabled pathogen inactivation, diagnostic biosensing, host-directed intervention, and virus-inspired therapeutic platforms. Emerging opportunities in antiviral drug discovery and artificial intelligence-assisted materials design are also discussed. In addition, key challenges associated with structural stability, biosafety, scalable fabrication, and clinical translation are highlighted. This Review provides an overview of current progress and outlines perspectives for the future development of MOF-based anti-pathogen technologies.

Indexed as

antiviral therapeuticsbiointerfacesbiomimetic deliverybiosensingimmune engineeringmetal–organic frameworks (MOFs)pathogen surveillanceprogrammable anti-pathogen systems

Identifiers

PMID42450601
PMCPMC13360019

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.