A Low Matrix Effects Analytical Strategy for Diazepam Analysis in Aquatic Products Through Immunomagnetic Beads Purification.

Xiaoyi Lou, Qi Wang, Changling Fang, Xuanyun Huang, Yongfu Shi, Dongmei Huang

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoyi LouEast China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China.

Qi WangEast China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China.

Changling FangEast China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China.

Xuanyun HuangEast China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China.ORCID 0000-0002-3872-5475

Yongfu ShiEast China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China.

Dongmei HuangEast China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China.ORCID 0000-0002-5698-8279

Funding

Central Public-interest Scientific Institution Basal Research Fund 2025XT0405Central Public-interest Scientific Institution Basal Research Fund 2026XT150202Hainan Provincial Natural Science Foundation of China 426MS0390

6 · The paper itself

Abstract

A low matrix effects (MEs) analytical strategy was developed for quantifying diazepam (DZP) in aquatic products by combining immunomagnetic bead (IMB)-based sample pretreatment with UPLC-MS/MS. The preparation conditions of IMBs, sample extraction, and purification were systematically optimized. Due to the weak MEs of this method, the quantification of DZP was carried out using a solvent-based calibration curve with an external standard solution. Good linearity was achieved over the range of 0.5-20 ng/mL with a correlation coefficient (R

Indexed as

aquatic productsdiazepamimmunomagnetic beadslow matrix effectsUPLC-MS/MS

Identifiers

PMID42450415

DOI10.3390/foods15132296

PMCPMC13360824

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.