Evidence map›Paper›PMID 42450405›Full record

ReviewFoods (Basel, Switzerland)2026

Cellulose Nanocrystal-Based Pickering Emulsions as Advanced Biomaterials for Food Bioactive Delivery: Chemical Modification, Synergistic Stabilization, and Functional Applications.

Haochen Ni, Kairu Li, Jiaqi Li, Suyu Li, Haoran Bai, Wenjing Dong, Fuqiang Zhang, Xinxin Yan, Jiaqi Guo

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haochen NiState Key Laboratory for Development and Utilization of Forest Food Resources and Co-Innovation Center for Efficient Processing and Utilization of Forest Products, Nanjing Forestry University, Nanjing 210037, China.
Kairu LiState Key Laboratory for Development and Utilization of Forest Food Resources and Co-Innovation Center for Efficient Processing and Utilization of Forest Products, Nanjing Forestry University, Nanjing 210037, China.
Jiaqi LiState Key Laboratory for Development and Utilization of Forest Food Resources and Co-Innovation Center for Efficient Processing and Utilization of Forest Products, Nanjing Forestry University, Nanjing 210037, China.
Suyu LiState Key Laboratory for Development and Utilization of Forest Food Resources and Co-Innovation Center for Efficient Processing and Utilization of Forest Products, Nanjing Forestry University, Nanjing 210037, China.
Haoran BaiState Key Laboratory for Development and Utilization of Forest Food Resources and Co-Innovation Center for Efficient Processing and Utilization of Forest Products, Nanjing Forestry University, Nanjing 210037, China.
Wenjing DongState Key Laboratory for Development and Utilization of Forest Food Resources and Co-Innovation Center for Efficient Processing and Utilization of Forest Products, Nanjing Forestry University, Nanjing 210037, China.
Fuqiang ZhangState Key Laboratory for Development and Utilization of Forest Food Resources and Co-Innovation Center for Efficient Processing and Utilization of Forest Products, Nanjing Forestry University, Nanjing 210037, China.
Xinxin YanState Key Laboratory for Development and Utilization of Forest Food Resources and Co-Innovation Center for Efficient Processing and Utilization of Forest Products, Nanjing Forestry University, Nanjing 210037, China.ORCID 0009-0006-4709-4675
Jiaqi GuoState Key Laboratory for Development and Utilization of Forest Food Resources and Co-Innovation Center for Efficient Processing and Utilization of Forest Products, Nanjing Forestry University, Nanjing 210037, China.

Funding

National Natural Science Foundation of China 32371811
6 · The paper itself

Abstract

Cellulose nanocrystals (CNCs) are renewable and biodegradable nanomaterials that can stabilize Pickering emulsions through steric hindrance and electrostatic repulsion. However, pristine CNCs show limited interfacial anchoring because of their strong hydrophilicity and high surface charge density, making the emulsions susceptible to coalescence, phase separation, and structural instability under environmental stresses. This review summarizes two major strategies for stabilizing and functionally regulating CNC-based Pickering emulsions: chemical modification and synergistic stabilization. Chemical modification regulates CNC surface charge, wettability, interfacial anchoring, and functional group composition through oxidation, amination, esterification, graft copolymerization, desulfation, and etherification, whereas synergistic stabilization constructs composite interfacial films or continuous-phase networks through noncovalent interactions between CNCs and proteins, polysaccharides, cyclodextrins, surfactants, inorganic nanomaterials, or functional molecules. The ability of these emulsion systems to compartmentalize oil-soluble bioactives within structured droplets also provides a basis for improving bioactive stability and release behavior in food-related formulations. These strategies improve emulsion stability and introduce antibacterial, antioxidant, responsive, and controlled-release properties, highlighting the potential of CNC-based Pickering emulsions in active food systems, including food preservation, active packaging, and the stabilization, protection, and release regulation of food bioactives. Remaining challenges in green preparation, structural regulation, release mechanisms, scalable production, and practical evaluation are also discussed.

Indexed as

cellulose nanocrystalschemical modificationfunctional applicationspickering emulsionssynergistic stabilization

Identifiers

PMID42450405
PMCPMC13362186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.