ReviewInternational journal of molecular sciences2026
ADNP Functions During Early Brain Development and Their Relevance to ASD and ADNP Syndrome.
Xiaonan Liu, Shiena Watanabe, Sierra Coleman, Vicky Shih, William R Telfer, Vasu D Kansagra, Lilit Drak, Laasya Reddy Pesaladinne, Diane Kim, Samridhi Sudan and 2 more
Abstract readReview
In one paragraphReview in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Xiaonan LiuDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.ORCID 0000-0002-3181-8310 Shiena WatanabeDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.ORCID 0000-0002-5227-7517 Sierra ColemanDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.ORCID 0000-0003-2267-9723 Vicky ShihDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
William R TelferDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Vasu D KansagraDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Lilit DrakDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Laasya Reddy PesaladinneDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Diane KimDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Samridhi SudanDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Anushka SinghalDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Kazuhito Toyo-OkaDepartment of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA.ORCID 0000-0002-0173-0430 Funding
Targeting the Pigment Epithelium-Derived Factor (PEDF) Signaling Pathway in Neurodevelopmental DisordersR21MH132839 · NIMH · DREXEL UNIVERSITY · PI TOYO-OKA, KAZUHITO · 2024 to 2025
$414kNIMH NIH HHS R21 MH132839NIMH NIH HHS R21MH132839United States Department of Defense AR220067
6 · The paper itselfAbstract
The Activity-Dependent Neuroprotective Protein (ADNP) is an important regulator of early brain development, especially during cortical neurogenesis and neurite formation. De novo point mutations or haploinsufficiency of the
Indexed as
Autism Spectrum DisorderBrainNerve Tissue ProteinsAnimalsHomeodomain ProteinsHumansNeurodevelopmentNeurogenesisADNP protein, humanHomeodomain ProteinsNerve Tissue ProteinsADNPADNP syndromeautism spectrum disordercortical developmentearly brain developmentmicrotubule dynamicsNAPneurite formationneurogenesis
Identifiers
PMID42450350
PMCPMC13361287
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