Evidence map›Paper›PMID 42450335›Full record

ArticleInternational journal of molecular sciences2026

Functional Analysis of the Histidine N-Methyltransferase SETD3 in Endometriosis.

Melanie Poloczek, Carolin Lisa Michaela Ludwig, Hanna Surmann, Theresa Strauß, Michael Gabriel, Matti Poutanen, Julia Oto, Ludwig Kiesel, Sebastian D Schäfer, Lars Hanker and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Melanie PoloczekDepartment of Gynecology and Obstetrics, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.ORCID 0000-0001-5260-1738
Carolin Lisa Michaela LudwigInstitute of Reproductive Biology, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Hanna SurmannDepartment of Gynecology and Obstetrics, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.ORCID 0009-0002-7708-7995
Theresa StraußDepartment of Gynecology and Obstetrics, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.
Michael GabrielResearch Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, 20520 Turku, Finland.ORCID 0000-0002-3870-7699
Matti PoutanenResearch Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
Julia OtoDepartment of Gynecology and Obstetrics, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.ORCID 0000-0003-3963-8661
Ludwig KieselDepartment of Gynecology and Obstetrics, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.ORCID 0000-0002-7247-9247
Sebastian D SchäferDepartment of Gynecology and Obstetrics, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.ORCID 0000-0002-8010-1463
Lars HankerDepartment of Gynecology and Obstetrics, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.
Joachim M WeitzelInstitute of Reproductive Biology, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.ORCID 0000-0002-4073-6691
Martin GötteDepartment of Gynecology and Obstetrics, University Hospital Muenster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.ORCID 0000-0003-2360-2496

Funding

Bundesministerium für Forschung, Technologie und Raumfahrt # 01EJ2401A ENDOFERTBundesministerium für Forschung, Technologie und Raumfahrt #01EJ2402B ENDO-PAINEU H2020- Marie Skłodowska-Curie Actions # 101008193 TRENDO
6 · The paper itself

Abstract

Endometriosis is a disease associated with pain symptoms and reduced fertility, characterized by the presence of endometrial tissue outside the uterus.

Indexed as

EndometriosisHistone MethyltransferasesAnimalsCell LineCell MovementCytoskeletonEndometriumFemaleHumansMiceHistone MethyltransferasesSETD3 protein, humanactin methylationcytoskeletonendometriosisinfertilityinvasive growthin vitro studymigrationSETD3

Identifiers

PMID42450335
PMCPMC13361998

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.