Evidence map›Paper›PMID 42450184›Full record

ArticleInternational journal of molecular sciences2026

A Novel Laboratory-Developed Test Using Multiplex qPCR to Further Personalize Tacrolimus Dosing.

Abhishek Chadha, Zhiwei Wang, Max Mamroth, John Hunter, Lin Xu, Sanghamitra Sahoo, Marc Rumpler, Alexandre Vlassov, Anna K Chikova

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abhishek ChadhaOne Lambda Inc., Part of Thermo Fisher Scientific Inc.©, West Hills, CA 91304, USA.
Zhiwei WangOne Lambda Inc., Part of Thermo Fisher Scientific Inc.©, West Hills, CA 91304, USA.ORCID 0009-0005-1973-9600
Max MamrothOne Lambda Inc., Part of Thermo Fisher Scientific Inc.©, West Hills, CA 91304, USA.ORCID 0009-0006-4863-0185
John HunterOne Lambda Laboratories, Part of Thermo Fisher Scientific Inc., West Hills, CA 91304, USA.
Lin XuOne Lambda Laboratories, Part of Thermo Fisher Scientific Inc., West Hills, CA 91304, USA.
Sanghamitra SahooOne Lambda Laboratories, Part of Thermo Fisher Scientific Inc., West Hills, CA 91304, USA.
Marc RumplerOne Lambda Laboratories, Part of Thermo Fisher Scientific Inc., West Hills, CA 91304, USA.
Alexandre VlassovOne Lambda Inc., Part of Thermo Fisher Scientific Inc.©, West Hills, CA 91304, USA.
Anna K ChikovaOne Lambda Inc., Part of Thermo Fisher Scientific Inc.©, West Hills, CA 91304, USA.ORCID 0009-0002-2369-073X

Funding

IDENTITY BY DESCENT MAPPING USING MICROARRAYSR01HG001880 · NHGRI · CHILDREN'S HOSP OF PHILADELPHIA · PI CHEUNG, VIVIAN G · 1999 to 2008
$2.8M
GENETICS LEGISLATION--SYNTAX, SCIENCE AND POLICYR01HG001889 · NHGRI · GEORGETOWN UNIVERSITY · PI GOSTIN, LAWRENCE O · 1998 to 2000
$377k
NHGRI NIH HHS R01 HG001880NHGRI NIH HHS R01 HG001889
6 · The paper itself

Abstract

Tacrolimus is an immunosuppressant drug commonly used in transplantation. Although multiple studies have demonstrated that polymorphisms in the

Indexed as

Cytochrome P-450 CYP3AImmunosuppressive AgentsMultiplex Polymerase Chain ReactionTacrolimusAllelesGenotypeGenotyping TechniquesHumansPolymorphism, Single NucleotidePrecision MedicineReproducibility of ResultsCYP3A5 protein, humanCytochrome P-450 CYP3AImmunosuppressive AgentsTacrolimusCYP3A5multiplexpharmacogeneticsqPCRtacrolimus

Identifiers

PMID42450184
PMCPMC13361501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.