From Monomers to Aggregates: The Influence of Redox State and Structure on the First Excited States of Eumelanin and Pheomelanin.

Joanna Waresiak, Filip Sagan, Mariusz Paweł Mitoraj, Tadeusz Sarna

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joanna WaresiakDepartment of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Krakow, Poland.ORCID 0009-0006-5763-2764

Filip SaganDepartment of Computational Methods in Chemistry, Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland.ORCID 0000-0001-5375-8868

Mariusz Paweł MitorajDepartment of Computational Methods in Chemistry, Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland.ORCID 0000-0001-5359-9107

Tadeusz SarnaDepartment of Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Krakow, Poland.ORCID 0000-0002-7693-5756

Funding

National Science Centre OPUS-2021/43/B/ST4/03255

6 · The paper itself

Abstract

Melanin pigments protect human tissues from ultraviolet and visible radiation, yet their phototoxic potential increases with oxidative degradation. This computational study investigates how the oxidation state influences the first excited states of eu- and pheomelanin using molecular models of varying complexity (monomers to tetramers, both covalently and non-covalently bonded). First, vertical and adiabatic electronic transitions were computed, and supramolecular interactions were characterized with the ETS-NOCV method. In eumelanin, oxidation drastically lowers the first triplet-state (T

Indexed as

MelaninsHumansModels, MolecularOxidation-ReductioneumelaninMelaninspheomelaninbenzothiazinesbenzothiazolesDHIDHICAETS-NOCVeumelaninexcited statespheomelanintriplets

Identifiers

PMID42450157

DOI10.3390/ijms27135886

PMCPMC13361419

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.