Evidence map›Paper›PMID 42450104›Full record

ArticleInternational journal of molecular sciences2026

Inhibition of CD38 by 78c Enhanced NAD

Jon Stephen Yarbrough, Subramanya Pandruvada, William D Hill, Hong Yu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jon Stephen YarbroughDepartment of Biomedical and Community Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Subramanya PandruvadaDepartment of Biomedical and Community Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0001-9568-7666
William D HillDepartment of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-8033-1605
Hong YuDepartment of Biomedical and Community Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-0930-6810

Funding

South Carolina IDeA Networks of Biomedical Research (SC INBRE V)P20GM103499 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI EDIE C GOLDSMITH · 2012 to 2026
$61.0M
South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
CD38 signaling in aging-associated immune responses induced by oral pathogensR21DE033977 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Hong Yu · 2025 to 2026
$415k
NCATS NIH HHS UL1 TR001450NIDCR NIH HHS R21 DE033977NIDCR NIH HHS R21DE033977NIGMS NIH HHS P20 GM103499NIH HHS 2P20GM103499-20NIH HHS UL1 TR001450
6 · The paper itself

Abstract

Old murine bone marrow-derived monocytes and macrophages (BMMs) display enhanced CD38 protein, a nicotinamide adenine dinucleotide (NAD

Indexed as

ADP-ribosyl Cyclase 1Alveolar Bone LossMembrane GlycoproteinsNADPeriodontitisAnimalsDisease Models, AnimalLiverMaleMiceMice, Inbred C57BLSpleenADP-ribosyl Cyclase 1Cd38 protein, mouseMembrane GlycoproteinsNADageCD38cytokineNAD+osteoclastogenesisperiodontitis

Identifiers

PMID42450104
PMCPMC13362391

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.