Evidence map›Paper›PMID 42450020›Full record

ArticleInternational journal of molecular sciences2026

Association of Selected Genetic Variants in CYP1A1, CYP2D6, NAT1 and NAT2 with Endometrial Cancer Risk: A Preliminary Case-Control Study.

Maciej Skrzypek, Monika Gogolewska, Andrzej Bieńkiewicz, Katarzyna Wójcik-Krowiranda, Ireneusz Majsterek, Jacek Kabziński

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maciej SkrzypekDepartment of Clinical Chemistry and Biochemistry, Medical University of Lodz, 92-215 Lodz, Poland.
Monika GogolewskaDepartment of Clinical Chemistry and Biochemistry, Medical University of Lodz, 92-215 Lodz, Poland.ORCID 0000-0002-0463-2473
Andrzej BieńkiewiczClinical Department of Gynecologic Oncology, Faculty of Health Sciences, Medical University of Lodz, 92-213 Lodz, Poland.
Katarzyna Wójcik-KrowirandaClinical Department of Gynecologic Oncology, Faculty of Health Sciences, Medical University of Lodz, 92-213 Lodz, Poland.
Ireneusz MajsterekDepartment of Clinical Chemistry and Biochemistry, Medical University of Lodz, 92-215 Lodz, Poland.
Jacek KabzińskiDepartment of Clinical Chemistry and Biochemistry, Medical University of Lodz, 92-215 Lodz, Poland.ORCID 0000-0002-8358-3947

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer risk may be influenced by genetic variation and altered expression of xenobiotic-metabolizing enzymes, yet their role in endometrial cancer remains incompletely understood. This study evaluated the association between four polymorphisms in xenobiotic metabolism-related genes

Indexed as

Arylamine N-AcetyltransferaseCytochrome P-450 CYP1A1Cytochrome P-450 CYP2D6Endometrial NeoplasmsGenetic Predisposition to DiseasePolymorphism, Single NucleotideAgedCase-Control StudiesFemaleGenetic Association StudiesHumansIsoenzymesMiddle AgedArylamine N-AcetyltransferaseCYP1A1 protein, humanCytochrome P-450 CYP1A1Cytochrome P-450 CYP2D6IsoenzymesN-acetyltransferase 1NAT2 protein, humanCYP1A1CYP2D6NAT1NAT2SNPuterine cancerxenobiotic metabolism

Identifiers

PMID42450020
PMCPMC13362363

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.