Evidence map›Paper›PMID 42450014›Full record

ArticleInternational journal of molecular sciences2026

Decoding the Microcin J25 Biosynthetic Cluster: Modulation of the

Emilse Masias, Juan I Ramirez, Lucía Lanza, Jorge A Lachenicht, María E Vázquez, Leonardo Acuña, Carlos J Minahk, Raul A Salomón

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emilse MasiasInstituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj", Facultad de Bioquímica, Química y Farmacia, UNT. Chacabuco 461, San Miguel de Tucumán T4000ILI, Argentina.ORCID 0000-0002-6802-7088
Juan I RamirezInstituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj", Facultad de Bioquímica, Química y Farmacia, UNT. Chacabuco 461, San Miguel de Tucumán T4000ILI, Argentina.ORCID 0009-0005-0524-4498
Lucía LanzaInstituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj", Facultad de Bioquímica, Química y Farmacia, UNT. Chacabuco 461, San Miguel de Tucumán T4000ILI, Argentina.ORCID 0009-0007-4624-5862
Jorge A LachenichtInstituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj", Facultad de Bioquímica, Química y Farmacia, UNT. Chacabuco 461, San Miguel de Tucumán T4000ILI, Argentina.
María E VázquezUnidad de Biotecnología y Protozoarios, Instituto de Patología Experimental "Dr. Miguel Ángel Basombrío", Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Salta, Salta A4408FVY, Argentina.ORCID 0000-0002-8202-3614
Leonardo AcuñaUnidad de Biotecnología y Protozoarios, Instituto de Patología Experimental "Dr. Miguel Ángel Basombrío", Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Universidad Nacional de Salta, Salta A4408FVY, Argentina.ORCID 0000-0001-5699-4583
Carlos J MinahkInstituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj", Facultad de Bioquímica, Química y Farmacia, UNT. Chacabuco 461, San Miguel de Tucumán T4000ILI, Argentina.ORCID 0000-0001-8765-8398
Raul A SalomónInstituto Superior de Investigaciones Biológicas (INSIBIO), CONICET-UNT, and Instituto de Química Biológica "Dr. Bernabé Bloj", Facultad de Bioquímica, Química y Farmacia, UNT. Chacabuco 461, San Miguel de Tucumán T4000ILI, Argentina.

Funding

Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación PICT 2019 N° 4126Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación PICT 2020 N° 2519Consejo Nacional de Investigaciones Científicas y Técnicas PIBAA 28720210100607COConsejo Nacional de Investigaciones Científicas y Técnicas PIE 2683National University of Tucumán PIUNT D721
6 · The paper itself

Abstract

A comprehensive analysis of the microcin J25 (MccJ25) biosynthetic gene cluster revealed a previously uncharacterized 96-base pair overlapping gene, designated

Indexed as

BacteriocinsEscherichia coliEscherichia coli ProteinsMultigene FamilyPromoter Regions, GeneticBase SequenceGene Expression Regulation, BacterialOperonBacteriocinsEscherichia coli ProteinsmicrocinEscherichia coligene expressiongreen fluorescent proteinMccJ25

Identifiers

PMID42450014
PMCPMC13361873

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.