Evidence map›Paper›PMID 42449992›Full record

ArticleInternational journal of molecular sciences2026

Enhanced Discrimination of Coronary Artery Disease Severity by Circulating Phoenixin-14: Evidence from a Clinical Laboratory Study.

İsmail Polat, Bekir Dagdeviren, Mehdi Karasu, Ömer Bedir, Suna Aydin, Elif Emre, Musa Sari, Özlem Seçen, Çetin Mirzaoglu, Suleyman Aydin

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

İsmail PolatDepartment of Cardiology, Fethi Sekin City Hospital, 23119 Elazig, Turkey.ORCID 0000-0001-5879-3494
Bekir DagdevirenDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Firat University, 23119 Elazig, Turkey.ORCID 0000-0003-3997-2969
Mehdi KarasuDepartment of Cardiology, Fethi Sekin City Hospital, 23119 Elazig, Turkey.ORCID 0000-0003-1713-3451
Ömer BedirDepartment of Cardiology, Adana City Training and Research Hospital, 01000 Adana, Turkey.ORCID 0000-0002-2508-6707
Suna AydinDepartment of Cardiovascular Surgery, Fethi Sekin City Hospital, 23119 Elazig, Turkey.
Elif EmreDepartment of Anatomy, Faculty of Medicine, Fırat University, 23119 Elazig, Turkey.ORCID 0000-0001-5659-3499
Musa SariDepartment of Biology (Molecular Biology), Faculty of Science, Sivas Cumhuriyet University, 58000 Sivas, Turkey.ORCID 0000-0002-6431-643X
Özlem SeçenDepartment of Cardiology, Fethi Sekin City Hospital, 23119 Elazig, Turkey.
Çetin MirzaogluDepartment of Cardiology, Fethi Sekin City Hospital, 23119 Elazig, Turkey.ORCID 0009-0002-9956-1029
Suleyman AydinDepartment of Biochemistry, Faculty of Medicine, Fırat University, 23119 Elazig, Turkey.ORCID 0000-0001-6162-3250

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early identification of anatomically significant coronary artery disease (CAD) remains a major clinical challenge despite advances in cardiovascular diagnostics. Novel circulating biomarkers may improve risk stratification and diagnostic discrimination beyond conventional parameters. We investigated the diagnostic utility of four emerging biomarkers-Phoenixin-14, Syntenin-1, Alamandine, and Cerebellin-1-for the assessment of CAD severity. In this prospective observational study, 90 participants undergoing coronary angiography were categorized into three groups: severe CAD (≥70% stenosis;

Indexed as

Coronary Artery DiseaseAgedBiomarkersCoronary AngiographyFemaleHumansMaleMiddle AgedProspective StudiesROC CurveSecretagoginsSeverity of Illness IndexSynteninsBiomarkersSCGN protein, humanSecretagoginsSynteninsAlamandinebiomarkersCerebellin-1coronary artery diseasecoronary stenosisdiagnostic accuracyPhoenixin-14ROC analysisstable angina pectorisSyntenin-1

Identifiers

PMID42449992
PMCPMC13361344

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.