Evidence map›Paper›PMID 42449660›Full record

ArticleCancers2026

Clinical Impact of Total Neoadjuvant Therapy Combined with Dose-Escalated Intensity-Modulated Radiotherapy for Lower Rectal Cancer: A Comparison with Conventional Neoadjuvant Chemoradiotherapy.

Mikio Kawamura, Yutaka Toyomasu, Shinji Yamashita, Hideharu Ieki, Hiroki Imaoka, Tadanobu Shimura, Takahito Kitajima, Yoshinaga Okugawa, Yoshiki Okita, Masaki Ohi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mikio KawamuraDepartment of Gastrointestinal and Pediatric Surgery, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.
Yutaka ToyomasuDepartment of Radiology, Mie University Hospital, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.
Shinji YamashitaDepartment of Gastrointestinal and Pediatric Surgery, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.
Hideharu IekiDepartment of Gastrointestinal and Pediatric Surgery, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.
Hiroki ImaokaDepartment of Gastrointestinal and Pediatric Surgery, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.
Tadanobu ShimuraDepartment of Gastrointestinal and Pediatric Surgery, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.
Takahito KitajimaDepartment of Genomic Medicine, Mie University Hospital, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.ORCID 0000-0003-3760-8514
Yoshinaga OkugawaDepartment of Genomic Medicine, Mie University Hospital, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.
Yoshiki OkitaDepartment of Gastrointestinal and Pediatric Surgery, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.
Masaki OhiDepartment of Gastrointestinal and Pediatric Surgery, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.
Yoshihito NomotoDepartment of Radiology, Mie University Hospital, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.ORCID 0009-0007-5521-9324
Yuji ToiyamaDepartment of Gastrointestinal and Pediatric Surgery, Mie University, 2-174 Edobashi, Tsu 514-8507, Mie, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

complete responseintensity modulated radiotherapylocally advanced rectal cancerneoadjuvant

Identifiers

PMID42449660
PMCPMC13359633

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.