Evidence map›Paper›PMID 42449639›Full record

ArticleCancers2026

Efficacy of Second-Line Lenvatinib After Atezolizumab-Bevacizumab and Durvalumab-Tremelimumab in Unresectable Hepatocellular Carcinoma: Association with Prior Immunotherapy Response.

Teiji Kuzuya, Hisanori Muto, Yoshihiko Tachi, Gakushi Komura, Takuji Nakano, Hiroyuki Tanaka, Kazunori Nakaoka, Kohei Funasaka, Mitsuo Nagasaka, Ryoji Miyahara and 1 more

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Teiji KuzuyaDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.ORCID 0000-0002-2229-990X
Hisanori MutoDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.
Yoshihiko TachiDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.ORCID 0000-0001-9799-2445
Gakushi KomuraDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.
Takuji NakanoDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.
Hiroyuki TanakaDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.
Kazunori NakaokaDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.ORCID 0000-0002-7407-1763
Kohei FunasakaDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.ORCID 0000-0002-3869-1420
Mitsuo NagasakaDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.
Ryoji MiyaharaDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.
Eizaburo OhnoDepartment of Gastroenterology and Hepatology, Fujita Health University, Toyoake 470-1192, Aichi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

atezolizumab plus bevacizumabdurvalumab plus tremelimumabhepatocellular carcinomaimmune checkpoint inhibitorlenvatinibsequential therapytreatment resistanceVEGF inhibition

Identifiers

PMID42449639
PMCPMC13359612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.